2025
Short-term exposure to ambient nitrogen dioxide and fine particulate matter and cause-specific mortality: A causal modeling approach in four regions
Marb A, Ma Y, Nobile F, Dubrow R, Kinney P, Stafoggia M, Chen K, Peters A, Breitner S. Short-term exposure to ambient nitrogen dioxide and fine particulate matter and cause-specific mortality: A causal modeling approach in four regions. Environmental Pollution 2025, 372: 126059. PMID: 40089139, DOI: 10.1016/j.envpol.2025.126059.Peer-Reviewed Original ResearchParticulate matterAir pollutionDaily NO<sub>2</sub> anShort-term air pollution exposureNitrogen dioxideDaily air pollution dataExposure to NO<sub>2</sub>Effects of air pollutionShort-term exposure to NO<sub>2</sub> anFine particulate matterTwo-pollutant modelsExposure to ambient nitrogen dioxideAmbient air pollutionAmbient particulate matterAir pollution dataAir pollution exposureCause-specific mortality ratesAmbient nitrogen dioxideRural populationCause-specific mortalityRespiratory mortality ratesMortality rateCause-specific deathCardiovascular mortality ratesPollution exposurePerinatal exposure to ambient fine particle air pollution and risk of childhood ewing sarcoma in a population-based case-control study in California (1988–2015)
Clark C, Wang R, Wiemels J, Metayer C, Deziel N, Ma X. Perinatal exposure to ambient fine particle air pollution and risk of childhood ewing sarcoma in a population-based case-control study in California (1988–2015). Environmental Health 2025, 24: 6. PMID: 40055781, DOI: 10.1186/s12940-025-01159-6.Peer-Reviewed Original ResearchConceptsHispanic childrenSarcoma riskControls frequency-matched to casesFrequency-matched to casesBirth yearPopulation-based case-control studyOdds ratioPM2.5 exposureConfidence intervalsAir pollution exposureCalifornia birth cohortNon-Hispanic childrenAmbient PM2.5 exposureFine particle air pollutionCase-control studyAmbient fine particulate matterHigher PM2.5 levelsMaternal residenceCancer riskMaternal educationPotential disparitiesBirth cohortHispanic ethnicityElevated oddsLinkage studiesA time-to-event analysis of the association between ambient air pollution and risk of spontaneous abortion using vital records in the U.S. state of Georgia (2005-2014)
Hsiao T, Gaskins A, Warren J, Darrow L, Strickland M, Russell A, Chang H. A time-to-event analysis of the association between ambient air pollution and risk of spontaneous abortion using vital records in the U.S. state of Georgia (2005-2014). American Journal Of Epidemiology 2025, kwaf019. PMID: 39894759, DOI: 10.1093/aje/kwaf019.Peer-Reviewed Original ResearchHazard ratioElemental carbonAmbient air pollution exposurePrenatal exposure windowsExposure to traffic-related pollutionResidential census tractsOrganic carbonEstimate hazard ratiosFetal death recordsRisk of spontaneous abortionAir pollution exposureElevated hazard ratiosAmbient air pollutionTraffic-related pollutantsNitrogen oxidesAir pollution regulationsResidential countyU.S. state of GeorgiaDeath recordsVital recordsCensus tractsTime-to-event analysisExposure windowsPollution exposureDaily concentrations
2024
Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study
Liao M, Zhang S, Wolf K, Bolte G, Laxy M, Schwettmann L, Peters A, Schneider A, Kraus U. Long-term associations between ambient air pollution and self-perceived health status: Results from the population-based KORA-Fit study. International Journal Of Hygiene And Environmental Health 2024, 264: 114513. PMID: 39719813, DOI: 10.1016/j.ijheh.2024.114513.Peer-Reviewed Original ResearchConceptsSelf-perceived healthLong-term air pollution exposureSelf-perceived health statusAir pollution exposurePoor SRHHealth statusAssociated with poor self-perceived healthPoor self-perceived healthPollution exposureInterquartile rangeLand-use regression modelsLogistic regressionGeocoded residential addressesParticle number concentrationFace-to-face interviewsCooperative Health ResearchEQ-5D index valueSelf-perceived stressAmbient air pollutionEQ-VAS scoresIQR increaseAir pollutionCross-sectional studyBody mass indexMultinomial logistic regressionOutdoor Air Pollution Exposure and Ovarian Cancer Incidence in a United States–Wide Prospective Cohort Study
Ish J, Chang C, Bookwalter D, Jones R, O’Brien K, Kaufman J, Sandler D, White A. Outdoor Air Pollution Exposure and Ovarian Cancer Incidence in a United States–Wide Prospective Cohort Study. Environmental Health Perspectives 2024, 132: 107701. PMID: 39352804, PMCID: PMC11444316, DOI: 10.1289/ehp14729.Peer-Reviewed Original ResearchEpigenome-wide association study of household air pollution exposure in an area with high lung cancer incidence.
Rahman M, Portengen L, Wong J, Breeze C, Blechter B, Hu W, Downward G, Zhang Y, Cardenas A, Ning B, Li J, Yang K, Hosgood H, Silverman D, Huang Y, Rothman N, Vermeulen R, Lan Q. Epigenome-wide association study of household air pollution exposure in an area with high lung cancer incidence. ISEE Conference Abstracts 2024, 2024 DOI: 10.1289/isee.2024.1088.Peer-Reviewed Original ResearchAssociation between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study
Sun P, Guo X, Ding E, Li C, Ren H, Xu Y, Qian J, Deng F, Shi W, Dong H, Lin E, Guo P, Fang J, Zhang Q, Zhao W, Tong S, Lu X, Pollitt K, Shi X, Tang S. Association between Personal Abiotic Airborne Exposures and Body Composition Changes among Healthy Adults (60–69 Years Old): A Combined Exposome-Wide and Lipidome Mediation Approach from the China BAPE Study. Environmental Health Perspectives 2024, 132: 077005. PMID: 39028628, PMCID: PMC11259245, DOI: 10.1289/ehp13865.Peer-Reviewed Original ResearchConceptsFat mass indicatorsHealthy older adultsBayesian kernel machine regressionVisceral fat areaOlder adultsPercent body fatBody compositionBody fat massExposome-wide association studyPrevention of chronic diseasesAir pollution exposureBody composition indicatorsMediation analysisInBody 770 deviceHealthy adultsAssociated with increased body fat massBody composition changesKernel machine regressionBayesian kernel machine regression modelsChronic diseasesPollution exposureBody fatAssociation studiesAdverse health effectsFat areaLong-term Air Pollution Exposure Is Associated With Increased Severity of Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry
Sack C, Wojdyla D, Macmurdo M, Gassett A, Kaufman J, Raghu G, Redlich C, Li P, Olson A, Leonard T, Todd J, Neely M, Snyder L, Gulati M, on behalf of the IPF-PRO Registry investigators. Long-term Air Pollution Exposure Is Associated With Increased Severity of Idiopathic Pulmonary Fibrosis in the IPF-PRO Registry. 2024, a1798-a1798. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a1798.Peer-Reviewed Original ResearchAssociation between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity
Shi W, Fang J, Ren H, Sun P, Liu J, Deng F, Zhang S, Wang Q, Wang J, Tong S, Tang S, Shi X. Association between exposure to chemical mixtures and epigenetic ageing biomarkers: Modifying effects of thyroid hormones and physical activity. Journal Of Hazardous Materials 2024, 469: 134009. PMID: 38492399, DOI: 10.1016/j.jhazmat.2024.134009.Peer-Reviewed Original ResearchPolycyclic aromatic hydrocarbonsChemical mixture exposureOrganophosphate estersPolyfluoroalkyl substancesMixture exposurePhysical activityAir pollution exposureExposure to chemical mixturesEffects of environmental chemicalsLevels of physical activityAromatic hydrocarbonsPollution exposureHealthy ageing strategiesAged care policyChemical mixturesHealthy older adultsEnvironmental chemicalsEpigenetic ageing biomarkersAdverse effects of environmental chemicalsAcceleration of population agingLifestyle factorsCare policyOlder adultsHormone homeostasisPhthalateOutdoor air pollution exposure and uterine cancer incidence in the Sister Study
Brown J, Ish J, Chang C, Bookwalter D, O’Brien K, Jones R, Kaufman J, Sandler D, White A. Outdoor air pollution exposure and uterine cancer incidence in the Sister Study. Journal Of The National Cancer Institute 2024, 116: 948-956. PMID: 38346713, PMCID: PMC11160506, DOI: 10.1093/jnci/djae031.Peer-Reviewed Original ResearchUterine cancer incidenceIncidence of uterine cancerCancer incidenceAir pollution exposureOutdoor air pollutionUterine cancerPollution exposureOutdoor air pollution exposureAnnual average air pollutant concentrationsHazard ratioSister Study participantsHealth effects associated with air pollutionReduce air pollution exposureConfidence intervalsVehicular traffic exposureAverage air pollutant concentrationsEstimate hazard ratiosUterine cancer casesCox proportional hazards modelsExposure to particulatesProportional hazards modelAir pollutionCancer casesStudy participantsTraffic exposure
2023
Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and immediate, short- and medium-term exposure to ambient air pollution: Results from the KORA cohort study. The Science Of The Total Environment 2023, 900: 165780. PMID: 37495154, DOI: 10.1016/j.scitotenv.2023.165780.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionExposure to air pollutionAmbient air pollutionAssociated with air pollutionExposure windowsBonferroni-corrected P value thresholdPopulation-based Cooperative Health ResearchShort-term exposure to air pollutionAir pollutionCooperative Health ResearchAir pollution exposureP-value thresholdAssociated with cardiopulmonary diseasesHealth researchLongitudinal associationsMedium-term exposureStudy participantsPollution exposureCohort studyCovariate-adjustedS4 surveyParticipantsAlterations of serum metabolitesSerum metabolitesPollutionAssociation Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark
Liew Z, Meng Q, Yan Q, Schullehner J, Hansen B, Kristiansen S, Voutchkova D, Olsen J, Ersbøll A, Ketzel M, Raaschou-Nielsen O, Ritz B. Association Between Estimated Geocoded Residential Maternal Exposure to Lithium in Drinking Water and Risk for Autism Spectrum Disorder in Offspring in Denmark. JAMA Pediatrics 2023, 177: 617-624. PMID: 37010840, PMCID: PMC10071398, DOI: 10.1001/jamapediatrics.2023.0346.Peer-Reviewed Original ResearchConceptsMaternal exposureOdds ratioStratified analysisNationwide population-based case-control studyPopulation-based case-control studyDanish Medical Birth RegistryDanish Psychiatric Central RegisterAutism spectrum disorderMedical Birth RegistryNovel environmental risk factorTenth Revision codesAdverse birth outcomesControl participantsMaternal prenatal exposureMaternal residential addressBirth yearCase-control studyPsychiatric Central RegisterMood-stabilizing effectsAir pollution exposureEnvironmental risk factorsInternational Statistical ClassificationWnt/β-catenin signalingStudy teamRelated Health ProblemsAir Pollution and Acute Kidney Injury in the U.S. Medicare Population: A Longitudinal Cohort Study
Lee W, Wu X, Heo S, Kim J, Fong K, Son J, Sabath M, Trisovic A, Braun D, Park J, Kim Y, Lee J, Schwartz J, Kim H, Dominici F, Al-Aly Z, Bell M. Air Pollution and Acute Kidney Injury in the U.S. Medicare Population: A Longitudinal Cohort Study. Environmental Health Perspectives 2023, 131: 047008. PMID: 37036790, PMCID: PMC10084931, DOI: 10.1289/ehp10729.Peer-Reviewed Original ResearchConceptsAcute kidney injuryFirst hospital admissionLongitudinal cohort studyHospital admissionKidney injuryCohort studyHazard ratioPopulation-based longitudinal cohort studyU.S. Medicare populationYears of ageAir pollution exposureNationwide Medicare dataPublic health policyCurrent National Ambient Air Quality StandardHealth care expendituresKidney functionDisease burdenMedicare populationMedicare dataLong-term exposureAdmissionPollution exposureHealth policyCare expendituresEffect estimates
2022
Short-term exposure to air pollution and mental disorders: a case-crossover study in New York City
Yoo E, Roberts J, Eum Y, Li X, Chu L, Wang P, Chen K. Short-term exposure to air pollution and mental disorders: a case-crossover study in New York City. Environmental Research Health 2022, 1: 015001. DOI: 10.1088/2752-5309/ac6439.Peer-Reviewed Original ResearchER visitsAir pollution exposureMental disordersShort-term exposureRace/ethnicityPollution exposureAmbient air pollution exposureEmergency room visitsConditional logistic regressionCase-crossover studySingle-day lagsCase-crossover designAge group 19Ambient air pollutionRoom visitsRelative riskPsychotic disordersLogistic regressionNew York CityDaily air pollution exposureSpecific disordersVisitsDisordersPpb increaseGroup 19Using time-resolved monitor wearing data to study the effect of clean cooking interventions on personal air pollution exposures
Gould C, Mujtaba M, Yang Q, Boamah-Kaali E, Quinn A, Manu G, Lee A, Ae-Ngibise K, Carrión D, Kaali S, Kinney P, Jack D, Chillrud S, Asante K. Using time-resolved monitor wearing data to study the effect of clean cooking interventions on personal air pollution exposures. Journal Of Exposure Science & Environmental Epidemiology 2022, 33: 386-395. PMID: 36274187, PMCID: PMC11815893, DOI: 10.1038/s41370-022-00483-0.Peer-Reviewed Original ResearchConceptsAir pollution exposurePersonal air pollution exposureControl armPM2.5 exposurePersonal PM2.5 exposurePollution exposureStudy armsLPG armPersonal exposureCooking interventionsAverage PM2.5 exposureExposure estimatesClean cooking interventionsCO exposureMean personal exposuresPregnant womenPersonal CO exposuresPersonal PM2.5Environmental exposuresAccelerometry dataPersonal monitorsInterventionExposureExposure parametersDirect associationInvestigation on associations between long-term air pollution exposure and osteoporotic fracture using nationwide cohort study data in South Korea
Heo S, Kim H, Kim S, Choe S, Byun G, Lee J, Bell M. Investigation on associations between long-term air pollution exposure and osteoporotic fracture using nationwide cohort study data in South Korea. ISEE Conference Abstracts 2022, 2022 DOI: 10.1289/isee.2022.o-op-031.Peer-Reviewed Original ResearchCirculating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers
Chen H, Zhang S, Yu B, Xu Y, Rappold A, Diaz-Sanchez D, Samet J, Tong H. Circulating microRNAs as putative mediators in the association between short-term exposure to ambient air pollution and cardiovascular biomarkers. Ecotoxicology And Environmental Safety 2022, 239: 113604. PMID: 35576800, PMCID: PMC9167781, DOI: 10.1016/j.ecoenv.2022.113604.Peer-Reviewed Original ResearchConceptsExposure to ambient air pollutionAmbient air pollutionExposure to air pollutionAir pollutionShort-term exposure to ambient PM<sub>2.5</sub> waExposure to ambient PM<sub>2.5</sub>Short-term exposure to ambient fine particulate matterShort-term exposure to ambient air pollutionAmbient PM<sub>2.5</sub>Exposure to ambient fine particulate matterAmbient fine particulate matterEffects of exposure to air pollutionAir quality monitoring stationsEffects of air pollution exposureFine particulate matterQuality monitoring stationsAir pollutant concentrationsResearch Triangle area of North CarolinaAir pollution exposureTriangle area of North CarolinaBlood lipid biomarkersResearch Triangle areaPollutant concentrationsParticulate matterPollution exposureAssociations between long term air pollution exposure and first hospital admission for kidney and total urinary system diseases in the US Medicare population: nationwide longitudinal cohort study
Lee W, Wu X, Heo S, Fong K, Son J, Sabath M, Braun D, Park J, Kim Y, Lee J, Schwartz J, Kim H, Dominici F, Bell M. Associations between long term air pollution exposure and first hospital admission for kidney and total urinary system diseases in the US Medicare population: nationwide longitudinal cohort study. BMJ Medicine 2022, 1: e000009. PMID: 36936557, PMCID: PMC10012859, DOI: 10.1136/bmjmed-2021-000009.Peer-Reviewed Original ResearchChronic kidney diseaseFirst hospital admissionUrinary system diseasesNationwide longitudinal cohort studyLongitudinal cohort studyHospital admissionSystem diseasesTotal kidneyCohort studyHazard ratioMedicare populationLong-term air pollution exposureSecondary outcome measuresPpb increaseUS Medicare populationZip codesAir pollution exposureKidney outcomesFirst admissionKidney diseaseDiagnosis codesNational HealthOutcome measuresMedicare feeUrinary systemLung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids.
Tong H, Zhang S, Shen W, Chen H, Salazar C, Schneider A, Rappold A, Diaz-Sanchez D, Devlin R, Samet J. Lung Function and Short-Term Ambient Air Pollution Exposure: Differential Impacts of Omega-3 and Omega-6 Fatty Acids. Annals Of The American Thoracic Society 2022, 19: 583-593. PMID: 34797737, DOI: 10.1513/annalsats.202107-767oc.Peer-Reviewed Original ResearchConceptsAmbient air pollutionAir pollutionParticulate matterShort-term exposure to ambient air pollutionShort-term ambient air pollution exposureNational Ambient Air Quality StandardsExposure to ambient air pollutionAmbient Air Quality StandardsHealth effects of air pollutionAmbient air pollution exposureExposure to air pollutionEffects of air pollutionFine particulate matterAir quality standardsAir pollution exposureAssociated with adverse respiratory effectsPollution exposureLevels of ozoneElevated ozone levelsN-3 FA intakePollutionQuality standardsOzone levelsAssociated with ozoneHealth effects
2021
Abstract 11443: Where NO2 Meets Omega-3 Polyunsaturated Fatty Acids: Health Impact of Short-Term Ambient Air Pollution Exposure in Healthy Adults
Tong H, Chen H, Zhang S, Shen W, Salazar C, Schneider A, Wyatt L, Rappold A, Diaz-Sanchez D, Devlin R, Samet J. Abstract 11443: Where NO2 Meets Omega-3 Polyunsaturated Fatty Acids: Health Impact of Short-Term Ambient Air Pollution Exposure in Healthy Adults. Circulation 2021, 144: a11443-a11443. DOI: 10.1161/circ.144.suppl_1.11443.Peer-Reviewed Original ResearchOmega-3 groupOmega-3 PUFA intakePUFA intakeHeart rate variabilityLung functionFlow-mediated dilation of brachial arteryHealthy adultsBlood lipidsDilatation of brachial arterySupplementation of omega-3 polyunsaturated fatty acidsExposure to ambient nitrogen dioxideAmbient air pollution exposurePolyunsaturated fatty acidsMarkers of coagulationNO 2 exposureIncreased lung functionFlow-mediated dilationNO 2 concentrationsExposure to air pollutionOmega-3 polyunsaturated fatty acidsOmega-3Air pollution exposureIncreased LF/HF ratioShort-term ambient air pollution exposureFrequency of heart rate variability
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