2023
Epidemiological Survey of Human Alphaherpesvirus 2 (HSV-2) Infection in Indigenous People of Dourados Municipality, Central Brazil
de Oliveira Bonfim F, Villar L, Croda J, da Silva S, Gonçalves C, de Castro V, de Rezende Romeira G, Cesar G, dos Santos Weis-Torres S, Horta M, Simionatto S, Motta-Castro A, de Paula V. Epidemiological Survey of Human Alphaherpesvirus 2 (HSV-2) Infection in Indigenous People of Dourados Municipality, Central Brazil. Tropical Medicine And Infectious Disease 2023, 8: 197. PMID: 37104324, PMCID: PMC10143357, DOI: 10.3390/tropicalmed8040197.Peer-Reviewed Original ResearchHSV-2 IgMHSV-2 transmissionHSV-2 infectionHealth access barriersIllicit drug abuseAdult Brazilian populationPublic health policyAppropriate intervention programsGenital ulcersGenital wartsUrethral dischargeExact prevalenceUrinary problemsHSV-2Used needlesSerologic testsContraceptive methodsActive adolescentsEpidemiological surveyBrazilian indigenous populationDrug usersCondom useDrug abuseHealth policyIndigenous populations
2022
HTLV infection in Brazil’s second-largest indigenous reserve
Amianti C, Bandeira L, Cesar G, Weis-Torres S, Tanaka T, Machado I, Gonçalves C, Simionatto S, Schnaufer E, Freitas F, Vallinoto A, Croda J, Motta-Castro A. HTLV infection in Brazil’s second-largest indigenous reserve. Scientific Reports 2022, 12: 16701. PMID: 36202887, PMCID: PMC9537150, DOI: 10.1038/s41598-022-21086-7.Peer-Reviewed Original ResearchConceptsHTLV infectionHTLV-1HTLV-2HTLV-1-associated myelopathyAdult T-cell leukemia/lymphomaHuman T-lymphotropic virus 1T-cell leukemia/lymphomaChronic inflammatory neurological diseaseHTLV-1 prevalenceInflammatory neurological diseasesHTLV-2 infectionAggressive malignant diseaseLeukemia/lymphomaEnzyme-linked immunosorbentMedian agePregnant populationMalignant diseaseBlood donorsStudy populationDrug usersNeurological diseasesCosmopolitan subtypeWestern blotSerum samplesDisease
2020
Trends of HIV, hepatitis C virus and syphilis seroprevalence among injection and non-injection drug users in southwestern China, 2010–2017
Jiang H, Zhang X, Zhang C, Lu R, Zhou C, Ouyang L, Xing H, Vermund SH, Shao Y, Ruan Y, Wu G, Qian HZ. Trends of HIV, hepatitis C virus and syphilis seroprevalence among injection and non-injection drug users in southwestern China, 2010–2017. AIDS Care 2020, 36: 612-617. PMID: 33345591, PMCID: PMC10767711, DOI: 10.1080/09540121.2020.1856320.Peer-Reviewed Original ResearchNon-injection drug usersHepatitis C virusDrug use behaviorsDrug usersHCV prevalenceC virusRisky drug use behaviorsTrends of HIVCross-sectional surveySyphilis seroprevalenceHIV prevalenceHIV transmissionPrevalence trendsPWIDDrug useHIVDisease preventionSexual contactUse behaviorsChi-squarePrevalenceSyphilisDrugsVirusPrimary riskTransmission of HIV and HCV within Former Soviet Union Countries
Aibekova L, Bexeitova A, Aldabergenova A, Hortelano G, Ge Z, Yi F, Shao Y, DeHovitz J, Vermund SH, Ali S. Transmission of HIV and HCV within Former Soviet Union Countries. Canadian Journal Of Gastroenterology And Hepatology 2020, 2020: 9701920. PMID: 32733822, PMCID: PMC7378597, DOI: 10.1155/2020/9701920.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusHepatitis C virusBlood-borne infectionsTransmission of HIVInjection drug useBlood-borne virusesHigh-risk populationInjection drug usersHarm reduction effortsOrigin of infectionImmunodeficiency virusC virusFSU countriesDrug usersDrug useHIV sequencesInfectionFormer Soviet Union countriesSoviet Union countriesVirusMajor populationPopulation
2019
Drug-induced stress responses and addiction risk and relapse
Wemm SE, Sinha R. Drug-induced stress responses and addiction risk and relapse. Neurobiology Of Stress 2019, 10: 100148. PMID: 30937354, PMCID: PMC6430516, DOI: 10.1016/j.ynstr.2019.100148.Peer-Reviewed Original ResearchDrug useDrug-induced stress responsesAddiction riskCo-occurring drug usePeripheral stress responsesAutonomic nervous system responsesNervous system responsesDrug use historyChronic drug useChronic drug usersAdrenal axisAcute effectsEvidence of alterationsDrug usersTonic levelsGlucocorticoid responseBinge/Prefrontal cortexDifferent drugsPsychoactive drugsDrug seekingDrugsStress responseRelapseHuman researchComparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka
Rathish D, Jayasumana C, Agampodi S. Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka. Journal Of Health, Population And Nutrition 2019, 38: 3. PMID: 30674350, PMCID: PMC6343272, DOI: 10.1186/s41043-019-0160-x.Peer-Reviewed Original ResearchConceptsDPP4 inhibitor usersCross-sectional studyDrug usersInhibitor usersDipeptidyl peptidase-4 inhibitor treatmentType 2 diabetes mellitusComparative cross-sectional studyBiochemical parametersIncretin-based therapiesMann-Whitney U testSignificant differencesHigh lipase levelsPrevious Asian studiesDPP4i groupDPP4i usersOral hypoglycaemicsALT levelsDiabetes mellitusLipase levelsDPP4 inhibitorsSerum lipaseInhibitor treatmentU testPancreatic amylaseHbA1c
2018
Assessing Individual and Disseminated Effects in Network-Randomized Studies
Buchanan AL, Vermund SH, Friedman SR, Spiegelman D. Assessing Individual and Disseminated Effects in Network-Randomized Studies. American Journal Of Epidemiology 2018, 187: 2449-2459. PMID: 30052722, PMCID: PMC6211234, DOI: 10.1093/aje/kwy149.Peer-Reviewed Original ResearchPerceptions of Health-Related Community Reentry Challenges among Incarcerated Drug Users in Azerbaijan, Kyrgyzstan, and Ukraine
Rozanova J, Morozova O, Azbel L, Bachireddy C, Izenberg JM, Kiriazova T, Dvoryak S, Altice FL. Perceptions of Health-Related Community Reentry Challenges among Incarcerated Drug Users in Azerbaijan, Kyrgyzstan, and Ukraine. Journal Of Urban Health 2018, 95: 508-522. PMID: 29728898, PMCID: PMC6095752, DOI: 10.1007/s11524-018-0256-4.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentSubstance use disordersUse disordersMethadone treatmentDrug usersPoor general healthGeneral health conditionPerception of healthAgonist treatmentDrug injectionGeneral healthHigh prevalenceHealth needsHealth-related tasksLogistic regressionMethadoneHealth conditionsPre-release planningDisordersTreatmentPublic healthTotal samplePrison settingDrugsHealth
2017
Hepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study
Zelenev A, Li J, Mazhnaya A, Basu S, Altice FL. Hepatitis C virus treatment as prevention in an extended network of people who inject drugs in the USA: a modelling study. The Lancet Infectious Diseases 2017, 18: 215-224. PMID: 29153265, PMCID: PMC5860640, DOI: 10.1016/s1473-3099(17)30676-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntiviral AgentsChemopreventionCitiesComputer SimulationDisease Transmission, InfectiousFemaleHepatitis CHumansMaleMiddle AgedModels, StatisticalPrevalenceSubstance Abuse, IntravenousSurveys and QuestionnairesTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsBaseline HCV prevalenceHepatitis C virusHCV prevalenceInjection partnersPrevention strategiesTreatment coverageTransmission of HCVHepatitis C virus (HCV) treatmentHCV elimination strategySuccessful HCV treatmentC virus treatmentInjection drug usersHCV treatment coverageAdditional network memberHCV treatmentActing antiviralsC virusChronic infectionVirus treatmentDrug usersPrevalenceDrug abuseDrugsNational InstitutePreventionHigh Prevalence of Treponema pallidum Infection in Brazilian Prisoners.
Correa ME, Croda J, Coimbra Motta de Castro AR, Maria do Valle Leone de Oliveira S, Pompilio MA, Omizolo de Souza R, Ferreira de Sá Queiroz JH, Esther da Silva K, Ko AI, Simionatto S. High Prevalence of Treponema pallidum Infection in Brazilian Prisoners. American Journal Of Tropical Medicine And Hygiene 2017, 97: 1078-1084. PMID: 28820706, PMCID: PMC5637599, DOI: 10.4269/ajtmh.17-0098.Peer-Reviewed Original ResearchConceptsActive syphilisSyphilis prevalenceHigh prevalenceBrazilian prisonersHuman immunodeficiency virus statusGenital ulcer diseaseIntravenous drug usersHigh-risk groupUnprotected sexual practicesMultivariable regression analysisCross-sectional studyActive syphilis prevalenceNew syphilis casesPopulation-based sampleDevelopment of syphilisCongenital infectionUlcer diseaseSyphilis testingRisk factorsVirus statusScreening programSerological statusSyphilis casesSevere formDrug usersMeasuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users
Shrestha R, Karki P, Altice FL, Dubov O, Fraenkel L, Huedo-Medina T, Copenhaver M. Measuring Acceptability and Preferences for Implementation of Pre-Exposure Prophylaxis (PrEP) Using Conjoint Analysis: An Application to Primary HIV Prevention Among High Risk Drug Users. AIDS And Behavior 2017, 22: 1228-1238. PMID: 28695388, PMCID: PMC5762432, DOI: 10.1007/s10461-017-1851-1.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisSex-related risk behaviorsHigh-risk drug usersAcceptability of PrEPHigh-risk PWUDPrimary HIV preventionHIV prevention approachesDrug treatment settingsKey risk populationsHIV-negative PWUDHigh acceptabilityHIV clinicPrEP acceptabilityHIV testingPrEP uptakeMethadone clinicsHIV preventionRisk populationsSide effectsTreatment settingsDrug usersPrEP attributesRisk behaviorsPrEPUnderserved populationsDeveloping an Integrated, Brief Biobehavioral HIV Prevention Intervention for High-Risk Drug Users in Treatment: The Process and Outcome of Formative Research
Shrestha R, Altice F, Karki P, Copenhaver M. Developing an Integrated, Brief Biobehavioral HIV Prevention Intervention for High-Risk Drug Users in Treatment: The Process and Outcome of Formative Research. Frontiers In Immunology 2017, 8: 561. PMID: 28553295, PMCID: PMC5425476, DOI: 10.3389/fimmu.2017.00561.Peer-Reviewed Original ResearchNeurocognitive impairmentHigh-risk drug usersBehavioral interventionsHigh-risk PWUDHIV prevention behavioral interventionBiobehavioral approachHIV risk reductionHIV prevention interventionsDrug treatment settingsFormative researchHIV prevention effortsTarget populationPrEP adherencePrEP uptakeRisk reduction outcomesHIV preventionDrug treatmentPrevention interventionsFocus groupsTreatment settingsDrug usersRecovery programStructured focus groupsRisk behaviorsTarget population membersInterest in use of mHealth technology in HIV prevention and associated factors among high-risk drug users enrolled in methadone maintenance program
Shrestha R, Karki P, Copenhaver M. Interest in use of mHealth technology in HIV prevention and associated factors among high-risk drug users enrolled in methadone maintenance program. AIDS Care 2017, 29: 1144-1148. PMID: 28478706, PMCID: PMC6081193, DOI: 10.1080/09540121.2017.1325439.Peer-Reviewed Original ResearchConceptsHigh-risk PWUDMethadone maintenance programHIV preventionMedication remindersHIV risk reduction informationRisk behaviorsSex-related risk behaviorsHigh-risk drug usersMHealth technologiesHIV prevention toolHIV risk reductionHIV prevention approachesHIV risk behaviorsDrug treatment settingsRisk Behavior AssessmentHIV prevention effortsHIV-negative PWUDUse of mHealthNew intervention strategiesDepressive symptomsTreatment settingsDrug usersHealthcare providersMultivariate analysisPrevention effortsIntent to Use Preexposure Prophylaxis (PrEP), HIV Risk Behaviors, and Self-Report Neurocognitive Symptoms by High-Risk Drug Users: A Mediation Analysis
Shrestha R, Karki P, Huedo-Medina TB, Copenhaver M. Intent to Use Preexposure Prophylaxis (PrEP), HIV Risk Behaviors, and Self-Report Neurocognitive Symptoms by High-Risk Drug Users: A Mediation Analysis. Journal Of The Association Of Nurses In AIDS Care 2017, 28: 612-621. PMID: 28478870, PMCID: PMC7451137, DOI: 10.1016/j.jana.2017.04.005.Peer-Reviewed Original ResearchConceptsHIV risk behaviorsNeurocognitive impairmentRisk behaviorsPreexposure prophylaxisSelf-reported neurocognitive symptomsHigh-risk drug usersHigh-risk PWUDPrEP uptakeNeurocognitive symptomsHIV riskDrug usersSimilar outcomesUnderserved populationsSignificant correlatesProphylaxisImportant unanswered questionsPreliminary evidencePrEPDissemination effortsMediation analysisUnanswered questionsVariables of interestHIVSymptomsCliniciansPrimary healthcare-based integrated care with opioid agonist treatment: First experience from Ukraine
Morozova O, Dvoriak S, Pykalo I, Altice FL. Primary healthcare-based integrated care with opioid agonist treatment: First experience from Ukraine. Drug And Alcohol Dependence 2017, 173: 132-138. PMID: 28242537, PMCID: PMC5545131, DOI: 10.1016/j.drugalcdep.2016.12.025.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCross-Sectional StudiesDelivery of Health Care, IntegratedFemaleHealth Services ResearchHIV InfectionsHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient DropoutsPatient SatisfactionPilot ProjectsPrimary Health CareQuality of LifeSubstance Abuse, IntravenousUkraineConceptsOpioid agonist therapyPrimary healthcare clinicsIntegrated carePHC staffHIV patientsHIV epidemicOAT patientsOpioid agonist treatmentStandard of careAddiction treatment settingsAgonist therapyObservational cohortMiddle-income countriesAgonist treatmentPrimary careComprehensive healthcare servicesPWIDHealthcare clinicsAddiction clinicPatientsTreatment settingsDrug usersPilot studyCareHealthcare servicesPredictors of HIV Risk Behavior in Iranian Women Who Inject Drugs
Habibi M, Farmanfarmaee S, Darharaj M, Khoshnood K, Matacotta J, O’Bryan J. Predictors of HIV Risk Behavior in Iranian Women Who Inject Drugs. Journal Of Drug Issues 2017, 47: 356-369. DOI: 10.1177/0022042617693383.Peer-Reviewed Original ResearchDrug-related HIV risk behaviorsHIV risk behaviorsRisk behaviorsPredictors of frequencyMethadone maintenance treatment programMaintenance treatment programDrug treatment centersHIV prevention programsRisk Behavior AssessmentBeck Depression Inventory-Second EditionHarm reduction servicesDrug use behaviorsSignificant predisposingInjection paraphernaliaRisk Behavior ScaleDrug usersPrevention programsIranian womenReduction servicesTreatment programDrugsWomenSelf-Efficacy ScalePredictorsPeer normsCorrelates of willingness to initiate pre-exposure prophylaxis and anticipation of practicing safer drug- and sex-related behaviors among high-risk drug users on methadone treatment
Shrestha R, Karki P, Altice FL, Huedo-Medina TB, Meyer JP, Madden L, Copenhaver M. Correlates of willingness to initiate pre-exposure prophylaxis and anticipation of practicing safer drug- and sex-related behaviors among high-risk drug users on methadone treatment. Drug And Alcohol Dependence 2017, 173: 107-116. PMID: 28214391, PMCID: PMC5366273, DOI: 10.1016/j.drugalcdep.2016.12.023.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisHIV risk reductionDrug injectionHIV riskRisk behaviorsHigh-risk drug usersHigh-risk PWUDOpioid-dependent personsHIV prevention approachesRecent risk behaviorsCross-sectional studyConsistent condom useHigh-risk behaviorsRisk reductionCorrelates of willingnessPrEP deliveryMethadone treatmentIndependent correlatesMethadone programsSafe drugElevated riskCasual partnersNeurocognitive impairmentDrug usersKey populationsModeling a theory-based approach to examine the influence of neurocognitive impairment on HIV risk reduction behaviors among drug users in treatment
Shrestha R, Huedo-Medina T, Copenhaver M. Modeling a theory-based approach to examine the influence of neurocognitive impairment on HIV risk reduction behaviors among drug users in treatment. Drug And Alcohol Dependence 2017, 171: e190. DOI: 10.1016/j.drugalcdep.2016.08.521.Peer-Reviewed Original Research
2016
Examining the Acceptability of mHealth Technology in HIV Prevention Among High-Risk Drug Users in Treatment
Shrestha R, Huedo-Medina TB, Altice FL, Krishnan A, Copenhaver M. Examining the Acceptability of mHealth Technology in HIV Prevention Among High-Risk Drug Users in Treatment. AIDS And Behavior 2016, 21: 3100-3110. PMID: 28025735, PMCID: PMC5484759, DOI: 10.1007/s10461-016-1637-x.Peer-Reviewed Original ResearchMeSH KeywordsAcquired Immunodeficiency SyndromeAdultCell PhoneConnecticutDelivery of Health CareDrug UsersFemaleHIV InfectionsHumansInternetMaleMethadoneNeurocognitive DisordersOpiate Substitution TreatmentPatient Acceptance of Health CarePrevalenceRisk FactorsRisk-TakingSexual BehaviorSmartphoneSubstance Abuse, IntravenousTelemedicineText MessagingConceptsSex-related risk behaviorsNeurocognitive impairmentDrug usersRisk behaviorsHIV-negative drug usersHigh-risk drug usersHigh-risk populationHigh-risk peopleHIV prevention effortsUse of mHealthMethadone clinicsHIV preventionHigh prevalenceMedication remindersHealth programsMHealth acceptancePrevention effortsHealth conditionsMHealth technologiesConvenience sampleDrugsStandardized assessmentReal-world acceptanceMobile healthPhone callsWillingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment
Shrestha R, Altice FL, Huedo-Medina TB, Karki P, Copenhaver M. Willingness to Use Pre-Exposure Prophylaxis (PrEP): An Empirical Test of the Information-Motivation-Behavioral Skills (IMB) Model among High-Risk Drug Users in Treatment. AIDS And Behavior 2016, 21: 1299-1308. PMID: 27990587, PMCID: PMC5380590, DOI: 10.1007/s10461-016-1650-0.Peer-Reviewed Original ResearchConceptsHigh-risk PWUDBehavioral skills modelCommunity-based methadone maintenance treatmentPre-exposure prophylaxis trialsSex-related HIV risk behaviorsHigh-risk drug usersPre-exposure prophylaxisIMB modelMethadone maintenance treatmentEfficacy of PrEPUse of PrEPHIV risk behaviorsKey risk populationsHealth behavior changeHIV acquisitionProphylaxis trialsHIV infectionMaintenance treatmentHIV preventionRisk populationsDrug usersRisk behaviorsPrEPPWUDIntervention development
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