2024
Proceedings from an international consensus meeting on ablation in urogenital diseases
Iezzi R, Contegiacomo A, De Filippis A, Gunn A, Atwell T, Mcclure T, Jing Z, Posa A, Scrofani A, Maresca A, Madoff D, Goldberg S, Kelekis A, Filippiadis D, Sala E, Ahmed M. Proceedings from an international consensus meeting on ablation in urogenital diseases. Insights Into Imaging 2024, 15: 267. PMID: 39514046, PMCID: PMC11549275, DOI: 10.1186/s13244-024-01841-2.Peer-Reviewed Original ResearchInternational Consensus MeetingAblation techniqueIntermediate-risk prostate cancerImage-guided ablation techniquesPreoperative surgical riskManagement of oncological diseasesRenal cell carcinomaConsensus meetingTraditional surgical treatmentGenitourinary tract diseaseFibroid SymptomCell carcinomaProstate cancerSurgical riskAblation therapyImprove patient outcomesTumor managementSurgical treatmentMechanism of actionEffective alternativeTherapeutic alternativeSite of applicationEffective treatmentUrogenital diseasesOncological diseases
2020
Modern best practice in the management of benign prostatic hyperplasia in the elderly
Bortnick E, Brown C, Simma-Chiang V, Kaplan S. Modern best practice in the management of benign prostatic hyperplasia in the elderly. Therapeutic Advances In Urology 2020, 12: 1756287220929486. PMID: 32547642, PMCID: PMC7273551, DOI: 10.1177/1756287220929486.Peer-Reviewed Original ResearchBenign prostatic hyperplasiaProstatic hyperplasiaManagement of benign prostatic hyperplasiaTreatment of benign prostatic hyperplasiaElderly malesUrinary tract symptomsMinimally invasive techniquesLong-term riskTransurethral resectionMedical therapySurgical optionsEjaculatory functionInvasive techniquesGeneral anesthesiaTreatment planningSide effectsGold standardPatientsProcedural techniquesDebilitating diseaseHyperplasiaEffective alternativeTreatmentMaleUroLift
2019
Moderate hypofractionation and stereotactic body radiation therapy in the treatment of prostate cancer
Beckta J, Nosrati J, Yu J. Moderate hypofractionation and stereotactic body radiation therapy in the treatment of prostate cancer. Urologic Oncology Seminars And Original Investigations 2019, 37: 619-627. PMID: 30738746, DOI: 10.1016/j.urolonc.2019.01.015.Peer-Reviewed Original ResearchConceptsModerate hypofractionationRadiation therapyStereotactic body radiation therapyProstate cancer radiation therapyTreatment of prostate cancerCancer radiation therapyReduced duration of treatmentDuration of treatmentStandard of careCurative intentProstate cancerHigh dosesHypofractionationReduced durationDaily sessionsFractionation schemeTherapyEffective alternativeTreatmentProstatePatientsCancerDoseMonthsCare
2018
Treating Sleep-Related Breathing Disorders
Won C, Mohsenin V, Kryger M. Treating Sleep-Related Breathing Disorders. 2018, 105-123. DOI: 10.1007/978-1-4939-8607-1_9.Peer-Reviewed Original ResearchPositive airway pressure therapySignificant symptomatic benefitAirway pressure therapySleep-disordered breathingMental health outcomesNeuropsychomotor functionsPAP therapyMainstay treatmentSymptomatic benefitPAP adherenceBreathing disordersPressure therapySide effectsHealth outcomesPatientsTherapyEffective alternativeAdherenceRobust evidenceTolerabilityBreathingSleepBazedoxifene–Conjugated Estrogens for Treating Endometriosis
Flores VA, Stachenfeld NS, Taylor HS. Bazedoxifene–Conjugated Estrogens for Treating Endometriosis. Obstetrics And Gynecology 2018, 132: 475-477. PMID: 29995747, DOI: 10.1097/aog.0000000000002739.Peer-Reviewed Original ResearchConceptsConjugated estrogensPelvic painTreatment optionsStage III endometriosisCyclic pelvic painFirst-line therapyReproductive-aged womenPotential treatment optionManagement of dysmenorrheaUnfavorable side effectsEndometriotic lesionsGynecologic disordersHormonal agentsMenopausal symptomsOvarian parametersSide effectsAnimal studiesEndometriosisEstrogenBazedoxifenePainEffective alternativeFailure rateAbnormal effectsDysmenorrheaFrom trust to skepticism: An in-depth analysis across age groups of adults with sickle cell disease on their perspectives regarding hydroxyurea
Sinha C, Bakshi N, Ross D, Krishnamurti L. From trust to skepticism: An in-depth analysis across age groups of adults with sickle cell disease on their perspectives regarding hydroxyurea. PLOS ONE 2018, 13: e0199375. PMID: 29949647, PMCID: PMC6021071, DOI: 10.1371/journal.pone.0199375.Peer-Reviewed Original ResearchConceptsSickle cell diseaseGroup 1 participantsGroup 2 participantsCell diseaseSide effectsAdult SCD patientsPatient-related factorsPotential side effectsAdult patientsSCD patientsHU usePatients' attitudesAge 31Age groupsAge 18PatientsYoung adultsEfficacySignificant differencesAdultsEffective alternativeDiseaseRiskParticipantsQualitative interviews
2015
Harnessing Case Isolation and Ring Vaccination to Control Ebola
Wells C, Yamin D, Ndeffo-Mbah ML, Wenzel N, Gaffney SG, Townsend JP, Meyers LA, Fallah M, Nyenswah TG, Altice FL, Atkins KE, Galvani AP. Harnessing Case Isolation and Ring Vaccination to Control Ebola. PLOS Neglected Tropical Diseases 2015, 9: e0003794. PMID: 26024528, PMCID: PMC4449200, DOI: 10.1371/journal.pntd.0003794.Peer-Reviewed Original ResearchConceptsRing vaccinationCase isolationContact tracingLimited initial supplyPost-exposure protectionMass vaccination campaignNon-pharmaceutical control measuresPublic health agenciesCandidate vaccinesVaccination campaignVaccinationCase contactsEbola casesEbola transmissionHealth agenciesIncidence dataLow efficacyVaccineEbola outbreakEffective alternativeMore contactEbolaSierra LeoneBeneficial supplementControl measures
2012
Pregestational Diabetes With Extreme Insulin Resistance
Zuckerwise LC, Werner EF, Pettker CM, McMahon-Brown EK, Thung SF, Han CS. Pregestational Diabetes With Extreme Insulin Resistance. Obstetrics And Gynecology 2012, 120: 439-442. PMID: 22825259, DOI: 10.1097/aog.0b013e31824fd27d.Peer-Reviewed Original ResearchConceptsSevere insulin resistanceInsulin resistanceGlycemic controlInsulin requirementsDiabetic patientsPregestational diabetes mellitusTreatment of patientsExtreme insulin resistancePregestational diabetesDiabetes mellitusRegular insulinPregnant womenPatientsHigh dosesInsulinPregnancyEffective alternativeWomenMellitusNonadherenceDiabetesDosesControlCervical Cancer Prevention in Low- and Middle-Income Countries: Feasible, Affordable, Essential
Sahasrabuddhe VV, Parham GP, Mwanahamuntu MH, Vermund SH. Cervical Cancer Prevention in Low- and Middle-Income Countries: Feasible, Affordable, Essential. Cancer Prevention Research 2012, 5: 11-17. PMID: 22158053, PMCID: PMC3586242, DOI: 10.1158/1940-6207.capr-11-0540.Peer-Reviewed Original ResearchConceptsCervical cancer preventionHuman immunodeficiency virusCervical cancerMiddle-income countriesCancer preventionPrevention servicesCervical cancer prevention servicesCancer prevention servicesCervical cancer screeningGynecologic issuesImmunodeficiency virusHuman papillomavirusCancer screeningEarly treatmentPelvic examHigh-income countriesWorldwide burdenCare deliveryNew casesScreening testHPVCancerLMICsEffective alternativePrevention
2011
ACR Appropriateness Criteria® Conservative surgery and Radiation – Stage I and II Breast Carcinoma
Bellon JR, Harris EE, Arthur DW, Bailey L, Carey L, Goyal S, Halyard MY, Horst KC, Moran MS, MacDonald SM, Haffty BG. ACR Appropriateness Criteria® Conservative surgery and Radiation – Stage I and II Breast Carcinoma. The Breast Journal 2011, 17: 448-455. PMID: 21790842, DOI: 10.1111/j.1524-4741.2011.01132.x.Peer-Reviewed Original ResearchConceptsRadiation therapySide effectsEarly-stage breast cancerLong-term side effectsAdjuvant radiation therapyAcute side effectsACR Appropriateness CriteriaWhole breast irradiationRisk of recurrenceAtherosclerotic heart diseasePartial breast irradiationMajority of womenConservative surgerySurvival benefitAppropriate patientsBreast conservationRandomized studyAppropriateness CriteriaHeart diseaseBreast carcinomaBreast cancerTherapyShort treatmentEffective alternativeTreatment
2007
Utility of the aortic fenestration technique in the management of acute aortic dissections.
Pradhan S, Elefteriades JA, Sumpio BE. Utility of the aortic fenestration technique in the management of acute aortic dissections. Annals Of Thoracic And Cardiovascular Surgery 2007, 13: 296-300. PMID: 17954985.Peer-Reviewed Original ResearchConceptsAortic replacement surgeryPercutaneous balloon fenestrationSurgical aortic fenestrationAcute aortic dissectionAortic fenestrationAortic dissectionBalloon fenestrationReplacement surgeryType B acute aortic dissectionB acute aortic dissectionLong-term effectivenessFenestration techniqueVessel ischemiaMedical managementHigh morbidityOptimal treatmentOpen fenestrationInvasive approachOperative strategySafe alternativeFenestrationPatientsSurgeryRecent dataEffective alternative
2005
Novel tissue adhesives to secure laser in situ keratomileusis flaps
Kang P, Carnahan M, Wathier M, Grinstaff M, Kim T. Novel tissue adhesives to secure laser in situ keratomileusis flaps. Journal Of Cataract & Refractive Surgery 2005, 31: 1208-1212. PMID: 16039499, DOI: 10.1016/j.jcrs.2004.10.067.Peer-Reviewed Original ResearchConceptsSitu keratomileusis flapsFlap dislocationDuke University Eye CenterHuman eye bank eyesSecond groupFlap edgeUniversity Eye CenterEye bank eyesTissue adhesiveMerocel spongeFlap complicationsLASIK flap complicationsEye CenterLASIK flapEpithelial ingrowthFlap adherenceFlapMicrokeratome systemScalpel bladeDye leakageFirst groupFluorescein dyeEffective alternativeRubbery consistencyFurther testing
2001
Treatment of Wilson’s disease: What are the relative roles of penicillamine, trientine, and zinc supplementation?
Schilsky M. Treatment of Wilson’s disease: What are the relative roles of penicillamine, trientine, and zinc supplementation? Current Gastroenterology Reports 2001, 3: 54-59. PMID: 11177695, DOI: 10.1007/s11894-001-0041-4.Peer-Reviewed Original ResearchConceptsWilson's diseaseSymptomatic patientsTreatment of choiceInitial therapyMaintenance therapyPregnant patientsCombination therapyZinc supplementationBest therapyNeurologic diseaseChelation therapyNext treatmentMedical treatmentPatientsTherapyDiseaseTrientineFurther studiesTreatmentMore effective alternativesEffective alternativeNew optionsPenicillamineLiverSupplementation
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