2001
Development of chronic colitis is dependent on the cytokine MIF
de Jong Y, Abadia-Molina A, Satoskar A, Clarke K, Rietdijk S, Faubion W, Mizoguchi E, Metz C, Sahli M, ten Hove T, Keates A, Lubetsky J, Farrell R, Michetti P, van Deventer S, Lolis E, David J, Bhan A, Terhorst C. Development of chronic colitis is dependent on the cytokine MIF. Nature Immunology 2001, 2: 1061-1066. PMID: 11668338, DOI: 10.1038/ni720.Peer-Reviewed Original ResearchMeSH KeywordsAdoptive TransferAnimalsAutoimmune DiseasesBone Marrow TransplantationChronic DiseaseColitisCrohn DiseaseDNA-Binding ProteinsFemaleHumansImmunization, PassiveLipopolysaccharidesMacrophage ActivationMacrophage Migration-Inhibitory FactorsMaleMiceMice, KnockoutModels, AnimalNuclear ProteinsRadiation ChimeraWeight LossConceptsMacrophage migration inhibitory factorCytokine macrophage migration inhibitory factorMIF-deficient miceCrohn's diseaseRole of MIFImmune systemPlasma MIF concentrationMucosal immune systemInnate immune cellsInnate immune systemChronic colitisMIF concentrationsExperimental colitisMIF productionMurine colitisImmune cellsColitisIntestinal bacteriaInhibitory factorDiseaseNew targetsMiceLipopolysaccharideCell typesPatients
1998
Effect of Heparin on Dextran Sulfate Sodium-Induced Colitis
Korzenik J, Hsu A, Robert M. Effect of Heparin on Dextran Sulfate Sodium-Induced Colitis. Digestive Diseases And Sciences 1998, 43: 1800-1805. PMID: 9724172, DOI: 10.1023/a:1018800207063.Peer-Reviewed Original ResearchConceptsBowel diseaseDextran Sulfate Sodium-Induced ColitisDextran sulfate-induced colitisSeverity of colitisSulfate-induced colitisInduction of colitisEffect of heparinMurine colitisSubcutaneous injectionWebster miceColitisHeparinized animalsHeparinAnticoagulant propertiesDiseaseMiceDextran sulfateOpposite effectSulfated polysaccharidesAnimalsDrinking waterSimilar pathwaysDosesSeverity
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