2021
Combinatorial Assembly of Modular Glucosides via Carboxylesterases Regulates C. elegans Starvation Survival
Wrobel C, Yu J, Rodrigues P, Ludewig A, Curtis B, Cohen S, Fox B, O’Donnell M, Sternberg P, Schroeder F. Combinatorial Assembly of Modular Glucosides via Carboxylesterases Regulates C. elegans Starvation Survival. Journal Of The American Chemical Society 2021, 143: 14676-14683. PMID: 34460264, PMCID: PMC8594405, DOI: 10.1021/jacs.1c05908.Peer-Reviewed Original ResearchMeSH KeywordsAcylationAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCarboxylic Ester HydrolasesGlucosidesMetabolomicsortho-AminobenzoatesStarvationConceptsStarvation conditionsCombinatorial assemblyPremier model systemRelated nematode speciesModel organismsStarvation survivalClose homologueGenome editingBiosynthetic roleNematode speciesBiological functionsComparative metabolomicsDeletion resultsAmino acidsFirst insightModel systemMetabolite libraryLipid metabolismAdult animalsAssemblyCRISPRBiosynthesisHomologuesDularOrganisms
2018
Nup159 Weakens Gle1 Binding to Dbp5 But Does Not Accelerate ADP Release
Wong EV, Gray S, Cao W, Montpetit R, Montpetit B, De La Cruz EM. Nup159 Weakens Gle1 Binding to Dbp5 But Does Not Accelerate ADP Release. Journal Of Molecular Biology 2018, 430: 2080-2095. PMID: 29782832, PMCID: PMC6003625, DOI: 10.1016/j.jmb.2018.05.025.Peer-Reviewed Original ResearchConceptsEssential DEAD-box proteinADP releaseDbp5's ATPase activityDEAD-box proteinsNucleotide exchange factorsDbp5 activityMRNA exportRNA metabolismExchange factorDbp5Cellular processesATPase cyclingNup159Gle1ATP affinityMechanochemical cycleATPase activityADPATP releaseDDX19NTPasesNucleoporinsDetailed characterizationRNARegulator
2001
Bile duct epithelia regulate biliary bicarbonate excretion in normal rat liver
Hirata K, Nathanson M. Bile duct epithelia regulate biliary bicarbonate excretion in normal rat liver. Gastroenterology 2001, 121: 396-406. PMID: 11487549, DOI: 10.1053/gast.2001.26280.Peer-Reviewed Original ResearchMeSH Keywords4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAcetylcholineAngiogenesis InhibitorsAnimalsAnti-Inflammatory Agents, Non-SteroidalBicarbonatesBileBile DuctsBiological TransportCalciumCyclic AMPCyclosporineDose-Response Relationship, DrugEnzyme InhibitorsEpithelial CellsGlucagonHepatic ArteryHepatic VeinsIn Vitro TechniquesLiverMaleNitrobenzoatesortho-AminobenzoatesRatsRats, Sprague-DawleySecretinVasoconstrictor AgentsVasodilator AgentsVasopressinsConceptsBiliary bicarbonate excretionEffect of secretinBicarbonate excretionHepatic arteryBiliary bicarbonateNormal rat liverDiphenylamine-2-carboxylic acidBile ductPortal veinRat liverEffects of acetylcholineBile duct epitheliumDose-dependent fashionFormation of bileBile flowBlood supplyBicarbonate exchangeDuct epitheliumAcetylcholineArteryAbstractTextExcretionCyclosporin A.LiverCholangiocytes
2000
Actin and Light Chain Isoform Dependence of Myosin V Kinetics †
De La Cruz E, Wells A, Sweeney H, Ostap E. Actin and Light Chain Isoform Dependence of Myosin V Kinetics †. Biochemistry 2000, 39: 14196-14202. PMID: 11087368, DOI: 10.1021/bi001701b.Peer-Reviewed Original Research
1992
Effects of formate and oxalate on volume absorption in rat proximal tubule
Wang T, Giebisch G, Aronson PS. Effects of formate and oxalate on volume absorption in rat proximal tubule. American Journal Of Physiology 1992, 263: f37-f42. PMID: 1636743, DOI: 10.1152/ajprenal.1992.263.1.f37.Peer-Reviewed Original ResearchConceptsLuminal perfusateProximal tubulesCapillary perfusateLate proximal tubuleRat proximal tubuleHCO3- Ringer's solutionPhysiological rangePeritubular capillariesChannel blockersStandard Ringer solutionPerfusateFluid absorptionStimulatory effectNaCl absorptionRinger's solutionTubulesEffect of formateBlockers
1973
Covalent attachment of fluorescent groups to the 5′-end of transfer RNA
Yang C, Söll D. Covalent attachment of fluorescent groups to the 5′-end of transfer RNA. Archives Of Biochemistry And Biophysics 1973, 155: 70-81. PMID: 4351348, DOI: 10.1016/s0003-9861(73)80010-4.Peer-Reviewed Original Research
1968
Antitumor activity and some pharmacologic properties of anthramycin methyl ether.
Adamson R, Hart L, DeVita V, Oliverio V. Antitumor activity and some pharmacologic properties of anthramycin methyl ether. Cancer Research 1968, 28: 343-7. PMID: 5641523.Peer-Reviewed Original Research
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