2025
Cannabis legalization and increasing cannabis use in the United States: Data from urine toxicology testing in emergency room patients
Fink D, Samples H, Malte C, Olfson M, Wall M, Alschuler D, Simpson T, Mannes Z, Saxon A, Hasin D. Cannabis legalization and increasing cannabis use in the United States: Data from urine toxicology testing in emergency room patients. International Journal Of Drug Policy 2025, 138: 104765. PMID: 40058102, PMCID: PMC11967342, DOI: 10.1016/j.drugpo.2025.104765.Peer-Reviewed Original ResearchConceptsUrine drug screensCannabis use disorderMedical cannabis lawsVeterans Health AdministrationCannabis useRecreational cannabis lawsRates of cannabis use disordersCannabis lawsEmergency departmentIndicators of cannabis useUrine toxicology testsIncreased cannabis useDifference-in-differences analysisLegalized cannabis useEmergency room patientsSelf-reported dataBinomial regression modelsED visitsED patientsHealth AdministrationCannabis involvementPatient samplesPatientsUse disorderCannabisUnderstanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review
Yilmaz S, Aryal K, King J, Bischof J, Hong A, Wood N, Gould Rothberg B, Hudson M, Heinert S, Wattana M, Coyne C, Reyes-Gibby C, Todd K, Lyman G, Klotz A, Abar B, Grudzen C, Bastani A, Baugh C, Henning D, Bernstein S, Rico J, Ryan R, Yeung S, Qdaisat A, Padela A, Madsen T, Liu R, Adler D. Understanding oncologic emergencies and related emergency department visits and hospitalizations: a systematic review. BMC Emergency Medicine 2025, 25: 40. PMID: 40045233, PMCID: PMC11883922, DOI: 10.1186/s12873-025-01183-2.Peer-Reviewed Original ResearchConceptsEmergency departmentEmergency visitsPredictors of ED usePeer-reviewed original research studiesSystematic reviewOncologic emergencyCancer incidence ratesCare delivery pathwaysGeriatric oncology researchManagement of oncologic emergenciesEmergency department visitsResultsThe search strategyTreatment side effectsOriginal research studiesCancer patientsVulnerable patient populationAcute careSingle-site studyWeb of ScienceCare venuesED useDepartment visitsHealth systemED visitsED presentationsUsing Radiology as a Screening Tool to Identify Intimate Partner Violence
Lenehan P, Tang A, Watane G, Gujrathi R, Park H, Gosangi B, Thomas R, Franco F, Patel K, Warsofsky I, Rosner B, Khurana B. Using Radiology as a Screening Tool to Identify Intimate Partner Violence. Journal Of The American College Of Radiology 2025, 22: 395-404. PMID: 40044319, PMCID: PMC11887577, DOI: 10.1016/j.jacr.2025.01.003.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesEmergency Service, HospitalFemaleHumansIncidenceIntimate Partner ViolenceMass ScreeningMiddle AgedRetrospective StudiesConceptsAdjusted incidence rate ratiosEmergency departmentRetrospective case-control studyImaging utilization patternsEvident injuriesCox proportional hazards regressionRace-matched controlsCase-control studyTime-to-event analysisProportional hazards regressionImaging utilizationIncidence rate ratiosCumulative incidenceAnatomical sitesScreening mammogramsHazards regressionOdds ratioImaging studiesIntimate partner violencePatientsInjury patternsLogistic regressionInjuryOrgan systemsPoisson regressionAdaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial
Iscoe M, Hooper C, Levy D, Buchanan L, Dziura J, Meeker D, Taylor R, D’Onofrio G, Oladele C, Sarpong D, Paek H, Wilson F, Heagerty P, Delgado M, Hoppe J, Melnick E. Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial. BMJ Open 2025, 15: e098072. PMID: 39979056, PMCID: PMC11842997, DOI: 10.1136/bmjopen-2024-098072.Peer-Reviewed Original ResearchConceptsClinical decision supportMultiphase optimization strategyOpioid use disorderEmergency departmentInitiation of buprenorphineClinical decision support usePlan-Do-Study-Act cyclesLearning health system approachPlan-Do-Study-ActClinical decision support toolHealth system approachAdaptive decision supportUse disorderDecision supportAddiction treatmentPeer-reviewed journalsBuprenorphine initiationOpioid use disorder treatment initiationOpioid-related mortalityIntervention componentsED settingClinician feedbackInstitute Institutional Review BoardTreatment of opioid use disorderParticipating sitesPalliative Care Initiated in the Emergency Department
Grudzen C, Siman N, Cuthel A, Adeyemi O, Yamarik R, Goldfeld K, Abella B, Bellolio F, Bourenane S, Brody A, Cameron-Comasco L, Chodosh J, Cooper J, Deutsch A, Elie M, Elsayem A, Fernandez R, Fleischer-Black J, Gang M, Genes N, Goett R, Heaton H, Hill J, Horwitz L, Isaacs E, Jubanyik K, Lamba S, Lawrence K, Lin M, Loprinzi-Brauer C, Madsen T, Miller J, Modrek A, Otero R, Ouchi K, Richardson C, Richardson L, Ryan M, Schoenfeld E, Shaw M, Shreves A, Southerland L, Tan A, Uspal J, Venkat A, Walker L, Wittman I, Zimny E. Palliative Care Initiated in the Emergency Department. JAMA 2025, 333: 599-608. PMID: 39813042, PMCID: PMC11836764, DOI: 10.1001/jama.2024.23696.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overDecision Support Systems, ClinicalEmergency Service, HospitalFemaleHospitalizationHumansMalePalliative CareConceptsInitiate palliative careLife-limiting illnessHealth care usePalliative carePostintervention periodPreintervention periodMulticomponent interventionCare useEmergency departmentOlder adultsHospital admissionRates of hospice useShort-term mortalitySecondary outcomesRate of hospital admissionsED clinical staffHome health useClinical decision supportNursing home patientsSimulation-based workshopGagne comorbidity scoreRate of admissionRisk of short-term mortalityHospice useIllness communicationClassifying Unstructured Text in Electronic Health Records for Mental Health Prediction Models: Large Language Model Evaluation Study
Cardamone N, Olfson M, Schmutte T, Ungar L, Liu T, Cullen S, Williams N, Marcus S. Classifying Unstructured Text in Electronic Health Records for Mental Health Prediction Models: Large Language Model Evaluation Study. JMIR Medical Informatics 2025, 13: e65454. PMID: 39864953, PMCID: PMC11884378, DOI: 10.2196/65454.Peer-Reviewed Original ResearchMeSH KeywordsElectronic Health RecordsEmergency Service, HospitalHumansMental DisordersMental HealthNatural Language ProcessingUnited StatesConceptsElectronic health recordsMental health termsHealth termsClinical expertsEmergency departmentHealth recordsPhysical healthMental healthElectronic health record systemsHealth care provider organizationsMental health-related problemsElectronic health record data setsCare provider organizationsMental health cliniciansMental health disordersHealth-related problemsED episodesHealth cliniciansRecords of individualsState-of-the-artDiagnostic codesHealth disordersHospital readmissionProvider organizationsMortality riskThe effect of inpatient brief cognitive-behavioral therapy for suicide prevention on post-discharge emergency department utilization: Secondary analysis of a randomized clinical trial
Diefenbach G, Collett S, Black S, Rudd M, Gueorguieva R, Tolin D. The effect of inpatient brief cognitive-behavioral therapy for suicide prevention on post-discharge emergency department utilization: Secondary analysis of a randomized clinical trial. General Hospital Psychiatry 2025, 93: 73-79. PMID: 39837259, DOI: 10.1016/j.genhosppsych.2025.01.007.Peer-Reviewed Original ResearchConceptsSubstance use disordersBrief cognitive-behavioral therapyCognitive-behavioral therapyED visitsSuicide preventionSecondary analysisEmergency departmentSuicide-related ED visitsHistory of suicide attemptsEmergency department utilizationElectronic medical record reviewPost-discharge emergency departmentMedical record reviewED utilizationPsychiatric readmissionTreatment effectsSuicide attemptsUse disorderRecord reviewSelf-reportRandomized clinical trialsGeneralized linear modelVisitsSuicidePost-discharge ED visitsThe Association Between Cost-Related Insulin Rationing and Health Care Utilization in U.S. Adults With Diabetes.
Borden C, Bakkila B, Nally L, Lipska K. The Association Between Cost-Related Insulin Rationing and Health Care Utilization in U.S. Adults With Diabetes. Diabetes Care 2025, 48: 400-404. PMID: 39746142, PMCID: PMC11870294, DOI: 10.2337/dc24-2117.Peer-Reviewed Original ResearchConceptsHealth care utilizationUrgent care visitsCare utilizationCare visitsU.S. adultsAssociated with health care utilizationNational Health Interview Survey respondentsAssociated with higher health care utilizationEmergency departmentHigher health care utilizationOdds of ED visitsRationing of health careCross-sectional studyNegative binomial regression modelsZero-inflated negative binomial regression modelsBinomial regression modelsHealth careED visitsSurvey weightsAge-stratifiedLogistic regressionSurvey respondentsVisitsRegression modelsAdults
2024
Factors Associated with Pediatric Drowning-Associated Lung Injury
Shenoi R, Crowe J, Dorfman S, Bergmann K, Mistry R, Hariharan S, Tavarez M, Wai S, Jones J, Langhan M, Ward C, McCallin T, Sethuraman U, Shah N, Mendez D, Wolpert K, Santos-Malave C, Ruttan T, Quayle K, Okada P, Bubolz B, Buscher J, McKee R, Mangold K, Wendt W, Thompson A, Hom J, Brayer A, Blackstone M, Brennan C, Russell W, Agarwal M, Khanna K, Louie J, Sheridan D, Camp E, Committee P. Factors Associated with Pediatric Drowning-Associated Lung Injury. The Journal Of Pediatrics 2024, 279: 114459. PMID: 39736377, DOI: 10.1016/j.jpeds.2024.114459.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCross-Sectional StudiesDrowningEmergency Service, HospitalFemaleHumansInfantInfant, NewbornLung InjuryMaleRetrospective StudiesRisk FactorsConceptsRisk factorsEmergency departmentCross-sectional study of childrenEmergency medical servicesPediatric emergency departmentCross-sectional studyAbnormal respiratory rateLung injuryPrehospital dataSpine injuriesAbnormal chest radiographic findingsED presentationsDrowning deathsMedical servicesPatient dispositionStudy of childrenChest radiographic findingsED courseAbnormal heart rateLogistic regressionShort-term outcomesAbnormal lung auscultationChest radiograph reportsRadiographic reportsOlder agePre-to-post COVID-19 pandemic trends in time from emergency department arrival to inpatient floor arrival: Door to floor time
Loza A, Sangal R, Gielissen K, Melnick E, Sankey C, Ostfeld-Johns S. Pre-to-post COVID-19 pandemic trends in time from emergency department arrival to inpatient floor arrival: Door to floor time. The American Journal Of Emergency Medicine 2024, 89: 187-189. PMID: 39731897, DOI: 10.1016/j.ajem.2024.12.051.Peer-Reviewed Original ResearchMeSH KeywordsAgedCOVID-19Emergency Service, HospitalFemaleHospitalizationHumansInpatientsMaleMiddle AgedPandemicsPatient AdmissionSARS-CoV-2Time FactorsEmergency Department Use Within 90 Days After Single-Level Posterior Cervical Foraminotomy.
Jayaram R, Oghenesume O, Day W, Kammien A, Grauer J. Emergency Department Use Within 90 Days After Single-Level Posterior Cervical Foraminotomy. Orthopedics 2024, 48: 51-56. PMID: 39699166, DOI: 10.3928/01477447-20241213-04.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCervical VertebraeEmergency Service, HospitalFemaleForaminotomyHumansMaleMiddle AgedUnited StatesConceptsSingle-level posterior cervical foraminotomyPosterior cervical foraminotomyElixhauser Comorbidity IndexCervical foraminotomyEmergency departmentPredictive factorsMultivariate analysisED visitsAcute postoperative periodPrimary ED diagnosisPatient agePostoperative periodPatient characteristicsSurgical siteFemale sexComorbidity indexIndications of traumaED diagnosisED useRisk factorsYounger agePatientsMultilevel proceduresForaminotomySurgeryImpact of the COVID-19 pandemic on hospital-based heart failure care in New South Wales, Australia: a linked data cohort study
McIntyre D, Quintans D, Kazi S, Min H, He W, Marschner S, Khera R, Nassar N, Chow C. Impact of the COVID-19 pandemic on hospital-based heart failure care in New South Wales, Australia: a linked data cohort study. BMC Health Services Research 2024, 24: 1364. PMID: 39516863, PMCID: PMC11545568, DOI: 10.1186/s12913-024-11840-0.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCohort StudiesCOVID-19Emergency Service, HospitalFemaleHeart FailureHospitalizationHumansMaleMiddle AgedNew South WalesPandemicsSARS-CoV-2ConceptsHeart failure careNew South WalesHospital admissionHealth service utilisationAdministrative health recordsPrimary diagnosis of heart failureData cohort studyRate of admissionPre-pandemicHealth of patientsSouth WalesCOVID-19 pandemicHospital utilisationService utilisationHealth recordsED presentationsMortality dataDiagnosis of heart failureCOVID-19 burdenEmergency departmentCohort studyPrimary diagnosisData collectionCareAustralian dataState and National Estimates of the Cost of Emergency Department Pediatric Readiness and Lives Saved
Newgard C, Lin A, Goldhaber-Fiebert J, Remick K, Gausche-Hill M, Burd R, Malveau S, Cook J, Jenkins P, Ames S, Mann N, Glass N, Hewes H, Fallat M, Salvi A, Carr B, McConnell K, Stephens C, Ford R, Auerbach M, Babcock S, Kuppermann N. State and National Estimates of the Cost of Emergency Department Pediatric Readiness and Lives Saved. JAMA Network Open 2024, 7: e2442154. PMID: 39485354, PMCID: PMC11530936, DOI: 10.1001/jamanetworkopen.2024.42154.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild, PreschoolCohort StudiesEmergency Service, HospitalFemaleHumansInfantInfant, NewbornMaleUnited StatesConceptsPediatric readinessED readinessEmergency departmentWeighted pediatric readiness scorePediatric livesCohort studyPediatric readiness scoreEmergency servicesUS emergency departmentsHigh emergency departmentAnnual hospital expendituresDistrict of ColumbiaNational annual costEmergency careReadiness scoresMain OutcomesNational estimatesChild deathsEligible childrenAged 0Hospital expendituresNational costUS costsUS statesChild's lifeEstimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias
Ouyang Y, Li F, Li X, Bynum J, Mor V, Taljaard M. Estimates of intra-cluster correlation coefficients from 2018 USA Medicare data to inform the design of cluster randomized trials in Alzheimer’s and related dementias. Trials 2024, 25: 732. PMID: 39478608, PMCID: PMC11523597, DOI: 10.1186/s13063-024-08404-2.Peer-Reviewed Original ResearchConceptsIntra-cluster correlation coefficientIntra-cluster correlation coefficient estimationSample size calculationED visitsMedicare dataMedicare fee-for-service beneficiariesEmergency departmentFee-for-service beneficiariesSize calculationDiagnosis of ADRDNational Medicare dataCluster randomized trialHospital referral regionsHospital service areasHealth care systemBackgroundCluster randomized trialsPopulation-level dataRandomized trialsDesign of cluster randomized trialsEvaluate interventionsReferral regionsCare systemICC estimatesADRDCorrelation coefficientImpact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisEmergency Department Visits Among Patients With Dementia Before and After Diagnosis
Gettel C, Song Y, Rothenberg C, Kitchen C, Gilmore-Bykovskyi A, Fried T, Brody A, Nothelle S, Wolff J, Venkatesh A. Emergency Department Visits Among Patients With Dementia Before and After Diagnosis. JAMA Network Open 2024, 7: e2439421. PMID: 39401040, PMCID: PMC11581500, DOI: 10.1001/jamanetworkopen.2024.39421.Peer-Reviewed Original ResearchHair Today, OR Tomorrow
Shah R, Grither A, Cohen S, Morales-Perez L, Rabiner J, Riera A. Hair Today, OR Tomorrow. Pediatric Emergency Care 2024, 41: 63-67. PMID: 39332825, DOI: 10.1097/pec.0000000000003238.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBezoarsChildChild, PreschoolEmergency Service, HospitalFemaleHairHumansMalePoint-of-Care SystemsStomachUltrasonographyTrends in visits, imaging, and diagnosis for emergency department abdominal pain presentations in the United States, 2007–2019
Wu R, Adjei‐Poku M, Kelz R, Peck G, Hwang U, Cappola A, Friedman A. Trends in visits, imaging, and diagnosis for emergency department abdominal pain presentations in the United States, 2007–2019. Academic Emergency Medicine 2024, 32: 20-31. PMID: 39313946, PMCID: PMC11726162, DOI: 10.1111/acem.15017.Peer-Reviewed Original ResearchConceptsOlder adultsAbdominal painED visitsComputed tomographyNational Hospital Ambulatory Medical Care SurveyEmergency departmentCT scanTest positivityAdult ED visitsPercentage of visitsAbdominal pain presentingNationally representative dataMiddle-aged adultsAbdominal CT scanCare SurveyPain presentationsAge-specificIncrease imaging ratesPractice patternsSurgical diagnosisAbdominal imagingDiagnostic pathwayRepresentative dataAcute pathologyVisitsApproach to Acute Dizziness/Vertigo in the Emergency Department: Selected Controversies Regarding Specialty Consultation
Puissant M, Giampalmo S, Wira C, Goldstein J, Newman-Toker D. Approach to Acute Dizziness/Vertigo in the Emergency Department: Selected Controversies Regarding Specialty Consultation. Stroke 2024, 55: 2584-2588. PMID: 39268603, PMCID: PMC11668186, DOI: 10.1161/strokeaha.123.043406.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseDizzinessEmergency Service, HospitalHumansReferral and ConsultationStrokeVertigoConceptsSpecialty consultationAcute dizzinessEmergency departmentDiagnosis of peripheral vestibular disordersEmergency department presentationsWell-trained providersPeripheral vestibular disordersLife-threatening diagnosisQuantify eye movementsVestibular disordersAcute dizziness/vertigoAccurate diagnosisDiagnostic approachStroke increasesDisposition and Follow-up for Low-Risk Febrile Infants: A Secondary Analysis of a Multicenter Study.
Kannikeswaran N, Spencer P, Tedford N, Truschel L, Chu J, Dingeldein L, Waseem M, Chow J, Lababidi A, Theiler C, Bhalodkar S, Yan X, Lou X, Fernandez R, Aronson P, Lion K, Gutman C. Disposition and Follow-up for Low-Risk Febrile Infants: A Secondary Analysis of a Multicenter Study. Hospital Pediatrics 2024, 14: e379-e384. PMID: 39113626, PMCID: PMC11358591, DOI: 10.1542/hpeds.2024-007850.Peer-Reviewed Original ResearchMeSH KeywordsAftercareCross-Sectional StudiesElectronic Health RecordsEmergency Service, HospitalFemaleFeverHumansInfantInfant, NewbornMalePatient DischargePrimary Health CareConceptsFebrile infantsFollow-upPrimary care providersElectronic health record documentationElectronic health recordsDischarged infantsEmergency departmentED dispositionLow riskAmerican Academy of Pediatrics guidelinesInvasive bacterial infectionsSecondary analysisCross-sectional studyMulticenter studyPost-discharge follow-upPediatric guidelinesWeekday visitsBacterial infectionsInfantsQuality of careAmerican AcademyMulticenterCare planningCare providersPatient-centered
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