2024
Transcranial optogenetic brain modulator for precise bimodal neuromodulation in multiple brain regions
Shin H, Nam M, Lee S, Yang S, Yang E, Jung J, Kim H, Woo J, Cho Y, Yoon Y, Cho I. Transcranial optogenetic brain modulator for precise bimodal neuromodulation in multiple brain regions. Nature Communications 2024, 15: 10423. PMID: 39613730, PMCID: PMC11607408, DOI: 10.1038/s41467-024-54759-0.Peer-Reviewed Original ResearchConceptsBrain regionsBrain modulesModulation of brain functionTranscranial brain stimulationMultiple brain regionsUpconversion particlesSymptoms of Parkinson's diseaseOptical crosstalkStudy of neural circuitsFood competition testBrain dysfunctionExternal light sourceLight sourcesBrain functionStudy of complex behaviorsSpatial resolutionNeural circuitsBrain disordersDevelopment of treatmentsOptogenetic techniquesBrain stimulationNeural populationsBrainParkinson's diseaseNeuromodulation
2023
Common and distinct neural correlates of emotional processing in individuals at familial risk for major depressive disorder and bipolar disorder: A comparative meta-analysis
Qin K, Pan N, Lei D, Zhang F, Yu Y, Sweeney J, DelBello M, Gong Q. Common and distinct neural correlates of emotional processing in individuals at familial risk for major depressive disorder and bipolar disorder: A comparative meta-analysis. Journal Of Affective Disorders 2023, 348: 97-106. PMID: 38113944, PMCID: PMC10846904, DOI: 10.1016/j.jad.2023.12.030.Peer-Reviewed Original ResearchMiddle occipital gyrusMajor depressive disorderHealthy controlsFamilial riskDepressive disorderBipolar disorderAbnormal functional activationPrecise prevention strategiesActivation patternsFunctional activation patternsDistinct neural phenotypesTask-based functional magnetic resonanceEmotional processingFunctional magnetic resonanceIllness onsetBrain dysfunctionFamilial predispositionMood disordersRisk relativesParahippocampal gyrusPrevention strategiesOccipital gyrusDistinct neural correlatesNeural phenotypesFunctional activationAn exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder
Worden B, Tolin D, Stevens M. An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder. Journal Of Affective Disorders 2023, 345: 410-418. PMID: 38706461, PMCID: PMC11068362, DOI: 10.1016/j.jad.2023.10.148.Peer-Reviewed Original ResearchCognitive behavioral therapyBrain activityEffective cognitive behavioral therapyCognitive-behavioral group therapyTreatment attendanceBrain dysfunctionFunctional magnetic resonanceDiscarding taskExecutive functioningAbnormal brain activityNeural predictorsHomework completionGroup therapyTreatment engagementHD patientsTreatment complianceHD treatmentPremotor areasActivity abnormalitiesPatient's abilityBrain regionsTherapeutic benefitTreatment retentionRegion activityPrior researchAn exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder.
Worden B, Tolin D, Stevens M. An exploration of neural predictors of treatment compliance in cognitive-behavioral group therapy for hoarding disorder. Journal Of Affective Disorders 2023 PMID: 39492520, DOI: 10.1016/j.jad.2023.10.148.Peer-Reviewed Original ResearchCognitive-behavioral therapyHoarding disorderBrain activityTreatment attendanceBrain dysfunctionCognitive-behavioral group therapyEffective cognitive-behavioral therapyAssociated with treatment attendanceFunctional magnetic resonanceAbnormal brain activityExecutive functionGroup therapyHomework completionTreatment retentionTreatment engagementBrain regionsActivation abnormalitiesRegional activityPremotor areasTreatment complianceInsulaCompliance variablesBrainPatient's abilityDisorders
2022
Developing a Standardized Approach to Grading the Level of Brain Dysfunction on EEG
Dhakar MB, Sheikh ZB, Desai M, Desai RA, Sternberg EJ, Popescu C, Baron-Lee J, Rampal N, Hirsch LJ, Gilmore EJ, Maciel CB. Developing a Standardized Approach to Grading the Level of Brain Dysfunction on EEG. Journal Of Clinical Neurophysiology 2022, 40: 553-561. PMID: 35239553, DOI: 10.1097/wnp.0000000000000919.Peer-Reviewed Original ResearchConceptsCerebral dysfunctionCritical Care EEG Monitoring Research ConsortiumInterrater agreementGrading scaleStandardized approachDegree of dysfunctionKappa statisticsStandardized grading scalePosterior dominant rhythmElectroencephalogram (EEG) background activityLevel of dysfunctionOverall interrater agreementNeuromonitoring toolsFleiss kappa statisticEEG findingsBrain dysfunction
2021
A graph theory‐based whole brain approach to assess mood state differences in adolescents and young adults with bipolar disorder
Goldman DA, Sankar A, Colic L, Villa L, Kim JA, Pittman B, Constable RT, Scheinost D, Blumberg HP. A graph theory‐based whole brain approach to assess mood state differences in adolescents and young adults with bipolar disorder. Bipolar Disorders 2021, 24: 412-423. PMID: 34665907, PMCID: PMC9016085, DOI: 10.1111/bdi.13144.Peer-Reviewed Original ResearchConceptsLenticular nucleusFunctional connectivityPrefrontal cortexMood statesYoung adultsLimited brain regionsAcute mood statesRight lenticular nucleusBipolar I disorderDorsal prefrontal cortexPrevious neuroimaging studiesWhole-brain approachTemporal functional connectivityFunctional magnetic resonanceLeft prefrontal cortexBrain dysfunctionContralateral homologuesHealthy controlsI disordersDepression scoresICD increasesRight cerebellumBipolar disorderEarly interventionBrain regionsCognitive decline following acute viral infections: literature review and projections for post-COVID-19
Damiano R, Guedes B, de Rocca C, de Pádua Serafim A, Castro L, Munhoz C, Nitrini R, Filho G, Miguel E, Lucchetti G, Forlenza O. Cognitive decline following acute viral infections: literature review and projections for post-COVID-19. European Archives Of Psychiatry And Clinical Neuroscience 2021, 272: 139-154. PMID: 34173049, PMCID: PMC8231753, DOI: 10.1007/s00406-021-01286-4.Peer-Reviewed Original ResearchConceptsAcute viral infectionViral infectionCognitive declineHuman cognitionCoronavirus disease 2019Possible cognitive declineAsymptomatic individualsBrain dysfunctionDisease 2019Human dementiaNeuropsychiatric issuesCognitive sequelaeAlzheimer's diseaseNarrative reviewInfectionInfectious diseasesHealth leadersDiseaseCOVID-19COVID-19 pandemicIndirect pathwaysCognitionCurrent knowledgeRecent findingsLiterature review
2017
Disruption of Brain–Heart Coupling in Sepsis
Admiraal MM, Gilmore EJ, Van Putten MJAM, Zaveri HP, Hirsch LJ, Gaspard N. Disruption of Brain–Heart Coupling in Sepsis. Journal Of Clinical Neurophysiology 2017, 34: 413-420. PMID: 28520632, DOI: 10.1097/wnp.0000000000000381.Peer-Reviewed Original Research
2014
Altered global brain signal in schizophrenia
Yang GJ, Murray JD, Repovs G, Cole MW, Savic A, Glasser MF, Pittenger C, Krystal JH, Wang XJ, Pearlson GD, Glahn DC, Anticevic A. Altered global brain signal in schizophrenia. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 7438-7443. PMID: 24799682, PMCID: PMC4034208, DOI: 10.1073/pnas.1405289111.Peer-Reviewed Original ResearchConceptsGlobal brain signalBrain dysfunctionHealthy subjectsBipolar patientsCortical powerBipolar disorderNeuropsychiatric conditionsFunctional MRIPatient samplesBrain connectivitySchizophreniaComplex neurobiologyDiagnostic specificityPatientsBrain signalsAlterationsDysfunctionSymptomsFindingsBaselineBrainMRI
2012
Impaired consciousness in epilepsy
Blumenfeld H. Impaired consciousness in epilepsy. The Lancet Neurology 2012, 11: 814-826. PMID: 22898735, PMCID: PMC3732214, DOI: 10.1016/s1474-4422(12)70188-6.Peer-Reviewed Original ResearchConceptsConsciousness systemQuality of lifeImpaired consciousnessEmotional healthDiverse seizure typesNormal human lifeComplex partial seizuresImpairment of consciousnessImproved treatment strategiesBehavioral testingBrain dysfunctionPartial seizuresSeizure typesTreatment strategiesEpileptic seizuresConsciousnessEpilepsySeizuresHuge consequencesNeuroimagingAlertnessAnatomical structuresSame setImpairmentLife
2011
Combined metopic and sagittal craniosynostosis: is it worse than sagittal synostosis alone?
Terner JS, Travieso R, Lee SS, Forte AJ, Patel A, Persing JA. Combined metopic and sagittal craniosynostosis: is it worse than sagittal synostosis alone? Neurosurgical FOCUS 2011, 31: e2. PMID: 21806341, DOI: 10.3171/2011.6.focus11100.Peer-Reviewed Original ResearchConceptsMonths of ageSmaller intracranial volumeBrain dysfunctionIntracranial volumeSagittal synostosisPatient groupVentricular volumeAge groupsSagittal craniosynostosisCSF spaceBrain volume reductionBrain tissue volumesSex-matched controlsSame age groupVolume reductionRetrospective chartFemale patientsForms of craniosynostosisSagittal synostosesPatientsYoung infantsBrain tissueCT reviewIntracranial compartmentDysfunctionThe Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis
Hannestad J, DellaGioia N, Bloch M. The Effect of Antidepressant Medication Treatment on Serum Levels of Inflammatory Cytokines: A Meta-Analysis. Neuropsychopharmacology 2011, 36: 2452-2459. PMID: 21796103, PMCID: PMC3194072, DOI: 10.1038/npp.2011.132.Peer-Reviewed Original ResearchConceptsMajor depressive disorderInflammatory cytokinesSerum levelsAntidepressant treatmentInterleukin-6Depressive symptomsIL-1βCytokine levelsDepressive episodeDiagnosis of MDDTumor necrosis factor alphaPharmacological antidepressant treatmentAntidepressant medication treatmentClasses of antidepressantsStratified subgroup analysisIL-1 betaNecrosis factor alphaNormalization of levelsReuptake inhibitorsMedication treatmentPharmacological treatmentSubgroup analysisBrain dysfunctionDepressive disorderFactor alpha
2000
Frontal lobe dysfunction and aggression Conceptual issues and research findings
Hawkins K, Trobst K. Frontal lobe dysfunction and aggression Conceptual issues and research findings. Aggression And Violent Behavior 2000, 5: 147-157. DOI: 10.1016/s1359-1789(98)00033-0.Peer-Reviewed Original Research
1998
Indicators of Brain Dysfunction Derived from Graphic Representations of the WAIS-III/WMS-III Technical Manual Clinical Samples Data: A Preliminary Approach to Clinical Utility
Hawkins K. Indicators of Brain Dysfunction Derived from Graphic Representations of the WAIS-III/WMS-III Technical Manual Clinical Samples Data: A Preliminary Approach to Clinical Utility. The Clinical Neuropsychologist 1998, 12: 535-551. DOI: 10.1076/clin.12.4.535.7236.Peer-Reviewed Original ResearchProcessing Speed IndexMemory indexWAIS-III/WMSWechsler Adult Intelligence ScaleVisual memory testsGeneral Memory IndexImmediate Memory IndexWechsler Memory ScaleAdult Intelligence ScaleBrain dysfunctionClinical sample dataMemory testModality effectMemory ScaleIntelligence ScaleThird editionBrain compromiseMemory deficiencySpeed indexVisual indexClinical samplesTechnical manualsClinical utilityIndex scoreAnxiety
1987
Clinical Features of Autistic Children with Setback Course in Their Infancy
Hoshino Y, Kaneko M, Yashima Y, Kumashiro H, Volkmar F, Cohen D. Clinical Features of Autistic Children with Setback Course in Their Infancy. Psychiatry And Clinical Neurosciences 1987, 41: 237-245. PMID: 3437611, DOI: 10.1111/j.1440-1819.1987.tb00407.x.Peer-Reviewed Original ResearchConceptsType of onsetAcquired groupClinical featuresHigh incidenceYears of ageInfantile autismSevere behavioral disordersPerinatal abnormalitiesFebrile convulsionsBrain dysfunctionIncidence rateHyperkinetic behaviorSelf-abusive behaviorEpileptic seizuresAutistic childrenBehavioral disordersIncidenceStereotypic behaviorOnsetDevelopmental levelAgeSubgroupsGroupChildrenPrognosis
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