2024
Gene Commonality in Arterial Circuits Throughout the Body
Harling L, Zafar M, Ziganshin B, Elefteriades J. Gene Commonality in Arterial Circuits Throughout the Body. Aorta 2024, 12: 008-012. PMID: 39532283, PMCID: PMC11606663, DOI: 10.1055/s-0044-1791667.Peer-Reviewed Original Research
2023
Drugs for spontaneous coronary dissection: a few untrusted options
Ilic I, Radunovic A, Timcic S, Odanovic N, Radoicic D, Dukuljev N, Krljanac G, Otasevic P, Apostolovic S. Drugs for spontaneous coronary dissection: a few untrusted options. Frontiers In Cardiovascular Medicine 2023, 10: 1275725. PMID: 38028484, PMCID: PMC10667692, DOI: 10.3389/fcvm.2023.1275725.Peer-Reviewed Original ResearchSpontaneous coronary artery dissectionDual antiplatelet therapyAntiplatelet therapyBeta-blockersRare cause of acute coronary syndromeLack of randomized studiesLeft ventricular ejection fractionSymptoms of heart failureCause of acute coronary syndromeRecurrence of SCADAngiotensin-converting enzyme inhibitorsVentricular ejection fractionSpontaneous coronary dissectionAngiotensin receptor blockersAcute coronary syndromeCoronary artery dissectionDecreased coronary flowLoop diureticsEjection fractionClinical presentationMineralocorticoid antagonistsP2Y12 inhibitorsRare causeRandomized studyArtery dissectionMultimodality Evaluation of Spontaneous Coronary Artery Dissection in a Patient With Connective Tissue Disease: A Case Report
Shah T, Shah N, Baldassarre L, Freed L, Mojibian H, Shah S. Multimodality Evaluation of Spontaneous Coronary Artery Dissection in a Patient With Connective Tissue Disease: A Case Report. Journal Of The Society For Cardiovascular Angiography & Interventions 2023, 2: 101125. PMID: 39129904, PMCID: PMC11308843, DOI: 10.1016/j.jscai.2023.101125.Peer-Reviewed Case Reports and Technical NotesGenetic Overlap of Spontaneous Dissection of Either the Thoracic Aorta or the Coronary Arteries
Jeoffrey S, Kalyanasundaram A, Zafar M, Ziganshin B, Elefteriades J. Genetic Overlap of Spontaneous Dissection of Either the Thoracic Aorta or the Coronary Arteries. The American Journal Of Cardiology 2023, 205: 69-74. PMID: 37591066, DOI: 10.1016/j.amjcard.2023.07.046.Peer-Reviewed Original ResearchConceptsCorresponding molecular pathwaysSpontaneous coronary artery dissectionGenetic overlapMolecular pathwaysGenome-wide association studiesGenetic commonalityGenetic variantsThoracic aortic dissectionIndependent genesGenetic pathwaysSmooth muscle cell functionGenetic methodsAortic dissectionMuscle cell functionAssociation studiesGenetic studiesSudden deathConnective tissue genesGenesTGFβ pathwayCausative genesCoronary artery dissectionTissue genesEarly-onset myocardial infarctionBiologic processes
2022
Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT
Zeng M, Zhao C, Bao X, Liu M, He L, Xu Y, Meng W, Qin Y, Weng Z, Yi B, Zhang D, Wang S, Luo X, Lv Y, Chen X, Sun Q, Feng X, Gao Z, Sun Y, Demuyakor A, Li J, Hu S, Guagliumi G, Mintz G, Jia H, Yu B. Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT. JACC Cardiovascular Imaging 2022, 16: 521-532. PMID: 36648054, DOI: 10.1016/j.jcmg.2022.10.023.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsOptical coherence tomographyTarget lesion revascularizationCardiac deathLesion revascularizationPredictors of Major Adverse Cardiac EventsAssociated with worse outcomesSpontaneous coronary artery dissectionClinical diagnosis of MIPrognosis of MINOCAMechanisms of MINOCAAdverse cardiac eventsNonobstructive coronary arteriesPrognosis of patientsCoronary artery dissectionDiagnosis of MIOCT findingsAtherosclerotic causeCardiac eventsClinical characteristicsClinical outcomesArtery dissectionComposite endpointMINOCACoronary spasmDepression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience)
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.Peer-Reviewed Original ResearchConceptsSpontaneous coronary artery dissectionPatient Health Questionnaire-9Coronary artery dissectionPSS-14 scoreArtery dissectionBaseline PHQ-9 scoreAcute myocardial infarction patientsCardiovascular risk factorsPHQ-9 scoresAcute myocardial infarctionMyocardial infarction patientsYears of agePerceived Stress Scale scoresStress Scale scoresLinear mixed-effects analysisSCAD casesVIRGO StudyQuestionnaire-9Infarction patientsMixed-effects analysisMyocardial infarctionSubgroup analysisRisk factorsRoutine screeningClinical acuityHealth status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience
Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.Peer-Reviewed Original ResearchConceptsSpontaneous coronary artery dissectionAcute myocardial infarctionAMI patientsCoronary artery dissectionYoung AMI patientsHealth status outcomesHealth status instrumentsSCAD patientsArtery dissectionMyocardial infarctionStatus outcomesPatientsOutcomesHousehold incomeCollege educationInfarction
2021
Sex Differences in Intracoronary Imaging and Functional Evaluation of Coronary Arteries
Velagapudi P, Altin S, Schneider M, Alasnag M. Sex Differences in Intracoronary Imaging and Functional Evaluation of Coronary Arteries. Current Cardiovascular Imaging Reports 2021, 14: 7. DOI: 10.1007/s12410-021-09557-3.Peer-Reviewed Original ResearchIntracoronary imagingArtery diseaseCoronary arteryNon-obstructive coronary artery diseaseSpontaneous coronary artery dissectionFunctional evaluationChronic coronary syndromeCoronary artery dissectionCoronary artery diseaseConventional coronary angiographyRecent FindingsThe diagnosisTreatment of womenOptical coherence tomographySex differencesSex-based differencesArtery dissectionCoronary syndromeMicrovascular dysfunctionCoronary angiographyMicrovascular functionClinical outcomesHyperemic responsePlaque characteristicsMyocardial infarctionBroad pathology
2020
Coronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection
Campbell KH, Tweet MS. Coronary Disease in Pregnancy: Myocardial Infarction and Spontaneous Coronary Artery Dissection. Clinical Obstetrics & Gynecology 2020, 63: 852-867. PMID: 32701519, PMCID: PMC10767871, DOI: 10.1097/grf.0000000000000558.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionSpontaneous coronary artery dissectionCoronary artery dissectionArtery dissectionMyocardial infarctionPregnancy-associated acute myocardial infarctionPregnancy-related maternal mortalityManagement of AMIMaternal cardiac deathsCoronary vasospasmNonatherosclerotic etiologyMaternal outcomesCardiac deathCoronary diseaseMultidisciplinary carePregnancy resultsMorbidity rateCoronary arteryMaternal mortalityGlobal improvementSubstantial proportionInfarctionPregnancyEtiologyPhysiological changesCoronary CT Angiography In Patients With Clinical Suspicion For Spontaneous Coronary Artery Dissection
Thondapu V, Goiffon R, Takigami A, Gupta S, Knyazev V, Depetris J, Wood M, Hedgire S, Ghoshhajra B. Coronary CT Angiography In Patients With Clinical Suspicion For Spontaneous Coronary Artery Dissection. Journal Of Cardiovascular Computed Tomography 2020, 14: s16. DOI: 10.1016/j.jcct.2020.06.006.Peer-Reviewed Original Research
2018
Update in Spontaneous Coronary Artery Dissection
Ingrassia J, Diver D, Vashist A. Update in Spontaneous Coronary Artery Dissection. Journal Of Clinical Medicine 2018, 7: 228. PMID: 30134627, PMCID: PMC6162848, DOI: 10.3390/jcm7090228.Peer-Reviewed Original Research
2016
Women and Chest Pain: Recognizing the Different Faces of Angina in the Emergency Department.
Safdar B, D'Onofrio G. Women and Chest Pain: Recognizing the Different Faces of Angina in the Emergency Department. The Yale Journal Of Biology And Medicine 2016, 89: 227-38. PMID: 27354848, PMCID: PMC4918863.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseAcute coronary syndromeChest painEmergency departmentMicrovascular dysfunctionED patientsCoronary artery endothelial dysfunctionCause of anginaCoronary artery dissectionCoronary artery spasmPersistent chest painRecurrent chest painSex-specific causesQuality of lifeArtery spasmArtery dissectionCoronary syndromeEndothelial dysfunctionMyocardial bridgingArtery diseasePoor functionCardinal symptomsAnginaPainPatients
2014
Gender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup
Safdar B, Nagurney JT, Anise A, DeVon HA, D'Onofrio G, Hess EP, Hollander JE, Legato MJ, McGregor AJ, Scott J, Tewelde S, Diercks DB. Gender‐specific Research for Emergency Diagnosis and Management of Ischemic Heart Disease: Proceedings from the 2014 Academic Emergency Medicine Consensus Conference Cardiovascular Research Workgroup. Academic Emergency Medicine 2014, 21: 1350-1360. PMID: 25413468, PMCID: PMC6402042, DOI: 10.1111/acem.12527.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseIschemic heart diseaseHeart diseaseCardiac ischemiaSymptomatic coronary artery diseaseObstructive coronary artery diseaseSex-specific pathophysiologyCoronary artery dissectionAge-matched menSex-specific riskPatient-centered outcomesPatient-provider communicationHealth care practitionersEmergency medical servicesGender-specific researchAcademic Emergency Medicine consensus conferencePerson meetingsBasic science researchArtery dissectionCardiovascular outcomesMonthly conference callsMicrovascular dysfunctionArtery diseasePatient outcomesCardiac biomarkers
2012
Acute myocardial infarction in the obstetric patient
Firoz T, Magee LA. Acute myocardial infarction in the obstetric patient. Obstetric Medicine 2012, 5: 50-57. PMID: 27579136, PMCID: PMC4989614, DOI: 10.1258/om.2011.011080.Peer-Reviewed Original ResearchAcute myocardial infractionObstetric patientsRisk factorsPre-existing cardiac risk factorsOutside of pregnancyCardiac risk factorsCoronary artery dissectionPregnancy-specific risk factorsAcute myocardial infarctionContext of pregnancyArtery dissectionAtherosclerotic diseaseRisk stratificationDrug therapyMaternal ageMyocardial infarctionPostpartum periodMyocardial infractionPregnancyPatientsDiagnostic testsOverall managementPhysiological changesFuture studiesRare event
2011
Coronary Artery Dissection and Perforation
Caixeta A, Nikolsky E, Lansky A, Mehran R, Dangas G. Coronary Artery Dissection and Perforation. 2011, 476-490. DOI: 10.1002/9781444319446.ch32.Peer-Reviewed Original Research
2009
An unusual case of spontaneous multi vessel coronary artery dissection in an elderly patient: a case report
Ozcan C, Cambi B, Remetz M. An unusual case of spontaneous multi vessel coronary artery dissection in an elderly patient: a case report. Cases Journal 2009, 2: 6645. PMID: 20184681, PMCID: PMC2827076, DOI: 10.4076/1757-1626-2-6645.Peer-Reviewed Original ResearchCoronary artery dissectionAcute coronary syndromeArtery dissectionMedical managementCoronary syndromeUnusual caseSignificant atherosclerotic coronary artery diseaseSudden-onset severe chest painSpontaneous coronary artery dissectionAtherosclerotic coronary artery diseaseSevere chest painUrgent cardiac catheterizationSuccessful medical managementPercutaneous coronary interventionCoronary artery diseaseEffective therapeutic optionST-segment elevationSudden cardiac deathYear old womanIschemic ST-segment elevationChest painAntiparkinson medicationCoronary interventionElderly patientsFocal dissection
2007
Angioplasty with stent implantation for the treatment of spontaneous coronary artery dissection
Ishii E, Chamié D, Staico R, Casas F, Feres F, Abizaid A, Mattos L, Chaves Á, Sousa A, Sousa J. Angioplasty with stent implantation for the treatment of spontaneous coronary artery dissection. Journal Of Transcatheter Interventions 2007, 15: 77-81. DOI: 10.1590/s2179-83972007000100015.Peer-Reviewed Original ResearchCoronary angiographyCircumflex arteryAdmitted with non-ST elevation myocardial infarctionTreatment of spontaneous coronary artery dissectionSpontaneous coronary artery dissectionNon-ST-elevation myocardial infarctionBaseline coronary angiographyHypertensive female patientCoronary artery dissectionLeft descending coronary arteryElevation myocardial infarctionDescending coronary arteryDissection extensionFemale patientsArtery dissectionST elevationPercutaneous treatmentStent implantationTIMI IICoronary arteryModerate lesionsMyocardial infarctionAngiographyCoronary angioplastyDistal flow
2003
Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil
Abbott JD, Curtis JP, Murad K, Kramer HM, Remetz MS, Setaro JF, Brennan JJ. Spontaneous Coronary Artery Dissection in a Woman Receiving 5-Fluorouracil. Angiology 2003, 54: 721-724. PMID: 14666962, DOI: 10.1177/000331970305400613.Peer-Reviewed Case Reports and Technical NotesConceptsSpontaneous coronary artery dissectionCoronary artery dissectionArtery dissectionMyocardial infarctionAcute ST-elevation myocardial infarctionST-elevation myocardial infarctionLeft anterior descending (LAD) arteryExtensive coronary dissectionAnterior descending (LAD) arteryPelvic radiation therapyCoronary dissectionPelvic radiationCoronary angiographyIntractable vomitingThrombolytic therapyCervical cancerHormonal changesRadiation therapyHemodynamic stressDissectionVomitingTherapyWomenVasospasmStenting
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