2025
Association of Primary Care Access with Health-Related ChatGPT Use: A National Cross-Sectional Survey
Ayo-Ajibola O, Julien C, Lin M, Riddell J, Duan N, Kravitz R. Association of Primary Care Access with Health-Related ChatGPT Use: A National Cross-Sectional Survey. Journal Of General Internal Medicine 2025, 1-8. PMID: 39930155, DOI: 10.1007/s11606-025-09406-9.Peer-Reviewed Original ResearchOnline health informationPrimary care accessCare accessSource of primary careNational cross-sectional surveyOnline health information sourcesSources of online health informationPrimary care relationshipsCross-sectional surveyNational survey of patientsSurvey of patientsMultiple logistic regressionNon-white raceNational Institutes of HealthPrimary careHealth characteristicsInstitutes of HealthHealth informationChi-square testCaring relationshipsDescriptive statisticsLogistic regressionPrimary languageHigher incomeNational survey
2023
Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke
Forman R, Okumu R, Mageid R, Baker A, Neu D, Parker R, Peyravi R, Schindler J, Sansing L, Sheth K, de Havenon A, Jasne A, Narula R, Wira C, Warren J, Sharma R. Association of Neighborhood-Level Socioeconomic Factors With Delay to Hospital Arrival in Patients With Acute Stroke. Neurology 2023, 102: e207764. PMID: 38165368, PMCID: PMC10834135, DOI: 10.1212/wnl.0000000000207764.Peer-Reviewed Original ResearchConceptsEmergency department arrival timesEmergency medical servicesLate presentationAcute ischemic stroke therapyYale-New Haven HospitalGuidelines-Stroke registryNeighborhood-level socioeconomic factorsPatient-level factorsRetrospective observational studyIschemic stroke therapyMixed-effects logistic regression modelNon-white patientsNon-white raceUnivariate logistic regressionNew Haven HospitalLogistic regression modelsHospital presentationTreatment ineligibilityStroke RegistryAcute strokeHospital arrivalStroke therapyUnivariate analysisObservational studyPatientsValidated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy
Kaman K, Dhodapkar M, Shabanova V, McCollum S, Factor J, Leeds S. Validated anxiety assessments among pediatric patients with peanut allergy on oral immunotherapy. Annals Of Allergy Asthma & Immunology 2023, 130: 657-663. PMID: 36738780, DOI: 10.1016/j.anai.2023.01.028.Peer-Reviewed Original ResearchConceptsPeanut oral immunotherapyOral immunotherapyNon-white racePeanut allergyAnxiety scoresOlder cohortProspective cross-sectional cohort studyCross-sectional cohort studyHigher mean anxiety scoresMean anxiety scoreDiagnosable anxietyCohort studyMale patientsPediatric patientsFemale patientsFood allergySimilar patientsHigh prevalenceHigher scoresLife measuresLow prevalencePatientsSeparation anxiety scoresElectronic survey questionnaireAllergy
2022
Trends of fecal calprotectin levels and associations with early life experience in preterm infants
Xu W, Zhang Y, Zhao W, Chen J, Maas K, Hussain N, Henderson W, Cong X. Trends of fecal calprotectin levels and associations with early life experience in preterm infants. Interdisciplinary Nursing Research 2022, 1: 36-42. PMID: 36590866, PMCID: PMC9766919, DOI: 10.1097/nr9.0000000000000006.Peer-Reviewed Original ResearchNeonatal intensive care unitFecal calprotectin levelsPreterm infantsMother's own milkFecal calprotectinFCP levelsFCP concentrationsNeonatal intensive care unit hospitalizationBiomarker of mucosal inflammationPainful proceduresMaturation of immune systemImmune systemChronic pain proceduresInfluence immune activationHigher severity of illness scoresNoninvasive surrogate biomarkerAcute painful proceduresPediatric gastrointestinal disordersSeverity of illness scoresImmature immune systemIntensive care unitChildren's medical centerNon-white raceNICU hospitalizationCalprotectin levelsCharacteristics of Chiropractic Patients in the Veterans Health Administration During the COVID-19 Pandemic: A Cross-Sectional Analysis
Roytman G, Cheung K, Bathulapalli H, Goertz C, Long C, Lisi A. Characteristics of Chiropractic Patients in the Veterans Health Administration During the COVID-19 Pandemic: A Cross-Sectional Analysis. Journal Of Manipulative And Physiological Therapeutics 2022, 45: 615-622. PMID: 37294219, PMCID: PMC10254439, DOI: 10.1016/j.jmpt.2023.04.002.Peer-Reviewed Original ResearchConceptsVeterans Health AdministrationCharlson Comorbidity IndexTelehealth visitsCross-sectional analysisComorbidity indexPatient characteristicsChiropractic careHealth AdministrationUS Veterans Health AdministrationRetrospective cross-sectional analysisCOVID-19 pandemicMarital statusNon-white raceYears of ageChiropractic patientsVHA patientsUnique patientsMusculoskeletal complaintsMusculoskeletal conditionsVisit typeMultinomial logistic regressionPatientsLatino ethnicityLogistic regressionVisitsTreatment response trajectories in residential PTSD programs for veterans: A national cohort investigation
Grau P, Sripada R, Pietrzak R, Ganoczy D, Harpaz-Rotem I. Treatment response trajectories in residential PTSD programs for veterans: A national cohort investigation. Journal Of Anxiety Disorders 2022, 92: 102645. PMID: 36334317, DOI: 10.1016/j.janxdis.2022.102645.Peer-Reviewed Original ResearchConceptsEvidence-based psychotherapiesThree-group trajectory modelTreatment outcomesTreatment responseTime of admissionPoor treatment outcomesPoor treatment responseNon-white raceResidential PTSD programsSubset of veteransPTSD treatment outcomesResidential PTSD treatmentPain severityCohort investigationPTSD careNational cohortFull cohortPTSD treatmentTherapeutic gainTreatment dropoutSymptom trajectoriesVeterans AffairsPTSD programTreatment response trajectoriesTreatment trajectoriesCorrelates of cognition among people with chronic heart failure and insomnia
Geer JH, Jeon S, O’Connell M, Linsky S, Conley S, Hollenbeak CS, Jacoby D, Yaggi HK, Redeker NS. Correlates of cognition among people with chronic heart failure and insomnia. Sleep And Breathing 2022, 27: 1287-1296. PMID: 36214945, PMCID: PMC10084469, DOI: 10.1007/s11325-022-02716-w.Peer-Reviewed Original ResearchConceptsChronic heart failureHigher body mass indexHeart failureBody mass indexQuality of lifeMass indexDaytime sleepinessNew York Heart Association class ICognitive impairmentSignificant risk factorsNon-white raceSelf-reported cognitive impairmentInsomnia Severity IndexSleep disturbance questionnaireCross-sectional analysisCognitive behavioral therapyFrequency of lapsesMedical comorbiditiesCommon comorbiditiesClinical factorsEjection fractionPulmonary diseaseMultivariable analysisRisk factorsSleep characteristicsThe All of Us Research Program: Data quality, utility, and diversity
Ramirez A, Sulieman L, Schlueter D, Halvorson A, Qian J, Ratsimbazafy F, Loperena R, Mayo K, Basford M, Deflaux N, Muthuraman K, Natarajan K, Kho A, Xu H, Wilkins C, Anton-Culver H, Boerwinkle E, Cicek M, Clark C, Cohn E, Ohno-Machado L, Schully S, Ahmedani B, Argos M, Cronin R, O’Donnell C, Fouad M, Goldstein D, Greenland P, Hebbring S, Karlson E, Khatri P, Korf B, Smoller J, Sodeke S, Wilbanks J, Hentges J, Mockrin S, Lunt C, Devaney S, Gebo K, Denny J, Carroll R, Glazer D, Harris P, Hripcsak G, Philippakis A, Roden D, Program T, Ahmedani B, Johnson C, Ahsan H, Antoine-LaVigne D, Singleton G, Anton-Culver H, Topol E, Baca-Motes K, Steinhubl S, Wade J, Begale M, Jain P, Sutherland S, Lewis B, Korf B, Behringer M, Gharavi A, Goldstein D, Hripcsak G, Bier L, Boerwinkle E, Brilliant M, Murali N, Hebbring S, Farrar-Edwards D, Burnside E, Drezner M, Taylor A, Channamsetty V, Montalvo W, Sharma Y, Chinea C, Jenks N, Cicek M, Thibodeau S, Holmes B, Schlueter E, Collier E, Winkler J, Corcoran J, D’Addezio N, Daviglus M, Winn R, Wilkins C, Roden D, Denny J, Doheny K, Nickerson D, Eichler E, Jarvik G, Funk G, Philippakis A, Rehm H, Lennon N, Kathiresan S, Gabriel S, Gibbs R, Rico E, Glazer D, Grand J, Greenland P, Harris P, Shenkman E, Hogan W, Igho-Pemu P, Pollan C, Jorge M, Okun S, Karlson E, Smoller J, Murphy S, Ross M, Kaushal R, Winford E, Wallace F, Khatri P, Kheterpal V, Ojo A, Moreno F, Kron I, Peterson R, Menon U, Lattimore P, Leviner N, Obedin-Maliver J, Lunn M, Malik-Gagnon L, Mangravite L, Marallo A, Marroquin O, Visweswaran S, Reis S, Marshall G, McGovern P, Mignucci D, Moore J, Munoz F, Talavera G, O'Connor G, O'Donnell C, Ohno-Machado L, Orr G, Randal F, Theodorou A, Reiman E, Roxas-Murray M, Stark L, Tepp R, Zhou A, Topper S, Trousdale R, Tsao P, Weidman L, Weiss S, Wellis D, Whittle J, Wilson A, Zuchner S, Zwick M. The All of Us Research Program: Data quality, utility, and diversity. Patterns 2022, 3: 100570. PMID: 36033590, PMCID: PMC9403360, DOI: 10.1016/j.patter.2022.100570.Peer-Reviewed Original Research
2021
COVID-19 Outcomes and Genomic Characterization of SARS-CoV-2 Isolated From Veterans in New England States: Retrospective Analysis
Lee M, Sallah YH, Petrone M, Ringer M, Cosentino D, Vogels CBF, Fauver JR, Alpert TD, Grubaugh ND, Gupta S. COVID-19 Outcomes and Genomic Characterization of SARS-CoV-2 Isolated From Veterans in New England States: Retrospective Analysis. JMIRx Med 2021, 2: e31503. PMID: 35014989, PMCID: PMC8722526, DOI: 10.2196/31503.Peer-Reviewed Original ResearchSARS-CoV-2 infectionPeak disease severityCOVID-19 outcomesChart reviewMean ageDisease severityHigher comorbidity burdenRetrospective chart reviewSARS-CoV-2 RNACohort of veteransGeneral US populationNon-white raceCOVID-19 infectionManual chart reviewSARS-CoV-2Multivariate regression analysisO2 requirementsNon-white veteransSARS-CoV-2 lineagesComorbidity burdenVirologic factorsD614G substitutionMultiple SARS-CoV-2 lineagesVirologic characteristicsClinical outcomesGenetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States
Azar MM, Cohen E, Ma L, Cissé OH, Gan G, Deng Y, Belfield K, Asch W, Grant M, Gleeson S, Koff A, Gaston DC, Topal J, Curran S, Kulkarni S, Kovacs JA, Malinis M. Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States. Clinical Infectious Diseases 2021, 74: 639-647. PMID: 34017984, PMCID: PMC9012955, DOI: 10.1093/cid/ciab474.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsCases of PCPPneumocystis pneumoniaClinic visitsRisk factorsClinic exposureLow absolute lymphocyte countRisk of PCPAbsolute lymphocyte countFrequent clinic visitsPneumocystis jirovecii pneumoniaStrong risk factorNon-white raceCase-control analysisBelatacept groupMonthly infusionsTransplant recipientsBaseline characteristicsJirovecii pneumoniaLymphocyte countMultilocus sequence typingInterhuman transmissionRespiratory specimensUnivariate analysisEpidemiologic data
2020
National Analysis of Patients With Ulcerated Melanoma in the United States
Boczar D, Sisti A, RESTREPO DJ, HUAYLLANI MT, MANRIQUE OJ, Lu X, SPAULDING AC, BAGARIA SP, PARKER AS, FORTE AJ. National Analysis of Patients With Ulcerated Melanoma in the United States. Anticancer Research 2020, 40: 1055-1058. PMID: 32014953, DOI: 10.21873/anticanres.14042.Peer-Reviewed Original ResearchConceptsUlcerated melanomaNational Cancer DatabaseNon-white patientsNon-white raceZip codesYears of agePatient disparitiesPatient demographicsMelanoma patientsTumor characteristicsMale sexUnfavorable prognosisCancer DatabaseHigher oddsLower oddsPatientsMelanomaUlcerationFacility characteristicsLower educationOddsLow incomeEducation levelUrban countiesPresent studyPosttraumatic stress disorder symptom trajectories within the first year following emergency department admissions: pooled results from the International Consortium to predict PTSD
Lowe SR, Ratanatharathorn A, Lai BS, van der Mei W, Barbano AC, Bryant RA, Delahanty DL, Matsuoka YJ, Olff M, Schnyder U, Laska E, Koenen KC, Shalev AY, Kessler RC. Posttraumatic stress disorder symptom trajectories within the first year following emergency department admissions: pooled results from the International Consortium to predict PTSD. Psychological Medicine 2020, 51: 1129-1139. PMID: 32008580, PMCID: PMC8318129, DOI: 10.1017/s0033291719004008.Peer-Reviewed Original ResearchConceptsAssaultive injuriesPrior interpersonal traumaEmergency departmentFemale genderPosttraumatic stress disorder symptom trajectoriesSymptom trajectoriesClinician-administered PTSD scaleGeneral hospital emergency departmentDemographic characteristicsEmergency department admissionsLong-term symptomsProportion of participantsHospital emergency departmentNon-white raceLogistic regression analysisMultinomial logistic regression analysisPTSD symptom trajectoriesPosttraumatic stress disorder (PTSD) symptoms
2018
Undertreated emotional distress in older adults with cancer.
Kapo J, Canavan M, Presley C, Wang S, Feder S, Sheinfeld E, Kent E, Davidoff A. Undertreated emotional distress in older adults with cancer. Journal Of Clinical Oncology 2018, 36: 165-165. DOI: 10.1200/jco.2018.36.34_suppl.165.Peer-Reviewed Original ResearchDevelopment and Validation of a Clinical Score for Cardiovascular Risk Stratification of Long‐Term Childhood Cancer Survivors
Oikonomou EK, Athanasopoulou SG, Kampaktsis PN, Kokkinidis DG, Papanastasiou CA, Feher A, Steingart RM, Oeffinger KC, Gupta D. Development and Validation of a Clinical Score for Cardiovascular Risk Stratification of Long‐Term Childhood Cancer Survivors. The Oncologist 2018, 23: 965-973. PMID: 29593100, PMCID: PMC6156177, DOI: 10.1634/theoncologist.2017-0502.Peer-Reviewed Original ResearchConceptsLong-term childhood cancer survivorsChildhood cancer survivorsCardiovascular risk stratificationCardiovascular mortalityCancer survivorsRisk scoreCardiovascular riskRisk stratificationRisk of CVMTreatment-related adverse eventsAdverse cardiovascular eventsRisk stratification toolSimple risk scoreCongestive heart failureCumulative incidence rateEnd Results ProgramMedian time periodPopulation-based studyHistory of lymphomaHigh-risk groupLow-risk groupSimple clinical toolHistory of radiationNon-white raceHealth care providers
2017
Treatment guidelines and patterns of care in oral cavity squamous cell carcinoma: Primary surgical resection vs. nonsurgical treatment
Fujiwara RJT, Burtness B, Husain ZA, Judson BL, Bhatia A, Sasaki CT, Yarbrough WG, Mehra S. Treatment guidelines and patterns of care in oral cavity squamous cell carcinoma: Primary surgical resection vs. nonsurgical treatment. Oral Oncology 2017, 71: 129-137. PMID: 28688680, DOI: 10.1016/j.oraloncology.2017.06.013.Peer-Reviewed Original ResearchConceptsOral cavity squamous cell carcinomaNational Cancer Data BaseLate-stage diseasePrimary nonsurgical treatmentOral cavity malignancyNonsurgical treatmentSquamous cell carcinomaOverall survivalSurgical resectionCell carcinomaTreatment modalitiesNational Comprehensive Cancer Network Clinical Practice GuidelinesAcademic/research programMultimodality clinical trialsDefinitive radiation therapyImproved overall survivalDecreased overall survivalPrimary surgical resectionOral cavity cancerNon-randomized natureClinical practice guidelinesPatterns of careNon-white raceProportional hazards modelBinary logistic regression
2016
Gender differences in physical activity following acute myocardial infarction in adults: A prospective, observational study
Minges KE, Strait KM, Owen N, Dunstan DW, Camhi SM, Lichtman J, Geda M, Dreyer RP, Bueno H, Beltrame JF, Curtis JP, Krumholz HM. Gender differences in physical activity following acute myocardial infarction in adults: A prospective, observational study. European Journal Of Preventive Cardiology 2016, 24: 192-203. PMID: 27885060, DOI: 10.1177/2047487316679905.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAustraliaCardiac RehabilitationChi-Square DistributionExerciseExercise TherapyFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedMyocardial InfarctionOdds RatioPatient ComplianceProspective StudiesRisk FactorsSex FactorsSpainTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsAcute myocardial infarctionPost-acute myocardial infarctionMyocardial infarctionPhysical activityRegular physical activity participationYoung AMI Patients (VIRGO) studyPhysical activity recommendationsAmerican Heart AssociationPhysical activity trajectoriesNon-white raceMyocardial infarction recoveryPhysical activity participationGender differencesHospital dischargeHeart AssociationLifestyle behaviorsActivity recommendationsObservational studyInfarctionAustralian hospitalsTargeted interventionsOne monthPatientsTime pointsLonger duration
2015
Lack of Association Between Costs of Care and Overall Survival (OS) Among Medicare Beneficiaries with Myelodysplastic Syndromes (MDS) in the United States (US)
Zeidan A, Wang R, Davidoff A, Gore S, Soulos P, Huntington S, Gross C, Ma X. Lack of Association Between Costs of Care and Overall Survival (OS) Among Medicare Beneficiaries with Myelodysplastic Syndromes (MDS) in the United States (US). Blood 2015, 126: 873. DOI: 10.1182/blood.v126.23.873.873.Peer-Reviewed Original ResearchDisability Status ScoreOverall survivalMyelodysplastic syndromeMDS patientsCost of careStudy cohortLack of associationHistologic subtypeStatus scoreMedicare beneficiariesEnd Results-Medicare databaseProportional hazards regression modelsOverall study cohortMedian overall survivalOutcomes of patientsElixhauser comorbidity scoreDate of diagnosisEntire study cohortKaplan-Meier methodHazards regression modelsDisease-related costsNon-white raceEnd of studyDate of deathMedicare Part AClinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction
Garber AM, Mentz RJ, Al-Khalidi HR, Shaw LK, Fiuzat M, O’Connor C, Velazquez EJ. Clinical predictors and outcomes of patients with left ventricular thrombus following ST-segment elevation myocardial infarction. Journal Of Thrombosis And Thrombolysis 2015, 41: 365-373. PMID: 26202909, DOI: 10.1007/s11239-015-1252-0.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionElevation myocardial infarctionNon-white raceHF severityBaseline characteristicsClinical predictorsHeart failureIndependent predictorsMyocardial infarctionHeart rateCox proportional hazards regression modelProportional hazards regression modelsLeft ventricular thrombusLong-term mortalityOutcomes of patientsVentricular thrombus formationHazards regression modelsHigher heart rateEligible patientsInitial troponinCause mortalityLAD diseaseSTEMI patientsVentricular thrombusTransthoracic echocardiogram
2013
Breast conservation therapy for ductal carcinoma in situ (DCIS): does presentation of disease affect long-term outcomes?
Bai HX, Motwani SB, Higgins SA, Haffty BG, Wilson LD, Lannin DR, Evans SB, Moran MS. Breast conservation therapy for ductal carcinoma in situ (DCIS): does presentation of disease affect long-term outcomes? International Journal Of Clinical Oncology 2013, 19: 460-466. PMID: 23780727, DOI: 10.1007/s10147-013-0575-0.Peer-Reviewed Original ResearchConceptsBreast conservation treatmentLocal relapse-free survivalRelapse-free survivalSigns/symptomsLong-term outcomesDCIS patientsPhysical signs/symptomsTumor sizeER/PR/HERWorse long-term prognosisSignificant overall survival differenceAdjuvant hormone treatmentLong-term prognosisOverall survival differenceBreast conservation therapyLarger tumor sizeStatus of marginsNon-white racePresentation of diseaseMedian followClinicopathological differencesNodal involvementOverall survivalIndependent predictorsConservation therapyPredictors of Interest in an Alcohol Reduction Clinical Trial of Naltrexone among Undergraduates
Leeman RF, Corbin WR, Fucito LM, Urwin JW, O’Malley S. Predictors of Interest in an Alcohol Reduction Clinical Trial of Naltrexone among Undergraduates. Journal Of Addiction Research & Therapy 2013, 4: 151. PMID: 24511431, PMCID: PMC3917969, DOI: 10.4172/2155-6105.1000151.Peer-Reviewed Original ResearchClinical trialsPredictors of interestTrend-level predictorCurrent cigarette smokingNon-white raceCigarette smokingDrinking reductionsPast-year drinkersTreatment engagementHeavy drinkersReduction messagesAlcohol-related negative consequencesYoung adultsSignificant predictorsTrialsNaltrexonePredictorsRandom sampleDrinkersRegression modelsFull regression modelCounselingEquivalent levelsHigher numberMedications
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