2024
PCDHGB7 hypermethylation-based Cervical cancer Methylation (CerMe) detection for the triage of high-risk human papillomavirus-positive women: a prospective cohort study
Cao D, Yang Z, Dong S, Li Y, Mao Z, Lu Q, Xu P, Shao M, Pan L, Han X, Yuan J, Fan Q, Chen L, Wang Y, Zhu W, Yu W, Wang Y. PCDHGB7 hypermethylation-based Cervical cancer Methylation (CerMe) detection for the triage of high-risk human papillomavirus-positive women: a prospective cohort study. BMC Medicine 2024, 22: 55. PMID: 38317152, PMCID: PMC10845746, DOI: 10.1186/s12916-024-03267-5.Peer-Reviewed Original ResearchConceptsHigh-risk human papillomavirusHrHPV-positive womenHigh-risk human papillomavirus-positive womenCervical intraepithelial neoplasia grade 1Triage of hrHPV-positive womenCervical intraepithelial neoplasia grade 2Triage strategiesHuman papillomavirus-positive womenInternational Peace Maternity and Child Health HospitalMaternal and Child Health HospitalMortality of cervical cancerChild Health HospitalProspective cohort studyASC-USLSIL cytologyColposcopy referralHealth HospitalCytology testHuman papillomavirusOver-referralCervical cancerCohort studyMethodsA totalGrade 2Grade 1
2023
An Alternative to Cytology in Triaging Cisgender Men and Transgender Women With HIV for High-Resolution Anoscopy
Mudrinich S, Nguyen M, Blemur D, Wang X, Wang Y, Krishnamurti U, Mosunjac M, Flowers L. An Alternative to Cytology in Triaging Cisgender Men and Transgender Women With HIV for High-Resolution Anoscopy. Journal Of Lower Genital Tract Disease 2023, 28: 101-106. PMID: 38117565, DOI: 10.1097/lgt.0000000000000773.Peer-Reviewed Original ResearchConceptsHigh-risk human papillomavirus (hrHPV) testingLow CD4 countRisk factorsTriage toolAnal cytologyCD4 countTransgender womenAdult cisgender menHigh-Resolution AnoscopyHuman papillomavirus testingCisgender menPredictive risk factorsRetrospective cohort studySignificant risk factorsSociodemographic risk factorsNegative predictive valueNovel triage toolHrHPV positivityUnderwent cytologyHrHPV testingCohort studyAnal neoplasiaScreening patternsPredictive valueHIVComparison of Diagnostic and Triage Accuracy of Ada Health and WebMD Symptom Checkers, ChatGPT, and Physicians for Patients in an Emergency Department: Clinical Data Analysis Study
Fraser H, Crossland D, Bacher I, Ranney M, Madsen T, Hilliard R. Comparison of Diagnostic and Triage Accuracy of Ada Health and WebMD Symptom Checkers, ChatGPT, and Physicians for Patients in an Emergency Department: Clinical Data Analysis Study. JMIR MHealth And UHealth 2023, 11: e49995. PMID: 37788063, PMCID: PMC10582809, DOI: 10.2196/49995.Peer-Reviewed Original ResearchConceptsTriage accuracyEmergency departmentAda HealthSymptom checkersED physiciansEffective health careIndependent physiciansHealth care workersSelf-reported clinical dataSelf-reported dataTriage ratingsPhysician reviewTriage recommendationsHealth careCare workersDeidentified dataPatient useResearch assistantsDiagnostic decision support systemED diagnosisTriage resultsTriage of patientsPhysiciansTriageHealthAn AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model
Charkoftaki G, Aalizadeh R, Santos-Neto A, Tan W, Davidson E, Nikolopoulou V, Wang Y, Thompson B, Furnary T, Chen Y, Wunder E, Coppi A, Schulz W, Iwasaki A, Pierce R, Cruz C, Desir G, Kaminski N, Farhadian S, Veselkov K, Datta R, Campbell M, Thomaidis N, Ko A, Thompson D, Vasiliou V. An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model. Human Genomics 2023, 17: 80. PMID: 37641126, PMCID: PMC10463861, DOI: 10.1186/s40246-023-00521-4.Peer-Reviewed Original ResearchConceptsCOVID-19 patientsDisease severityViral outbreaksFuture viral outbreaksLength of hospitalizationIntensive care unitWorse disease prognosisLife-threatening illnessEffective medical interventionsCOVID-19Clinical decision treeGlucuronic acid metabolitesNew potential biomarkersHospitalization lengthCare unitComorbidity dataSerotonin levelsDisease progressionHealthy controlsPatient outcomesDisease prognosisPatient transferPatientsHealthcare resourcesPotential biomarkersCaregiver Satisfaction with Emergency Department Care for Pediatric Patients with Neurodevelopmental Disorders
Heyming T, Knudsen-Robbins C, Davis K, Moreno T, Martin S, Shelton S, Ehwerhemuepha L, Kain Z. Caregiver Satisfaction with Emergency Department Care for Pediatric Patients with Neurodevelopmental Disorders. Journal Of Developmental And Behavioral Pediatrics 2023, 44: e388-e393. PMID: 37205728, DOI: 10.1097/dbp.0000000000001193.Peer-Reviewed Original ResearchConceptsCaregivers of patientsED satisfactionNeurodevelopmental disordersMultivariable logistic regression modelElectronic medical record dataTenth Revision codesEmergency department careMedical record dataCohort sample sizeEmergency Severity IndexAttention-deficit/hyperactivity disorderEmergency department experienceLogistic regression modelsHealth care systemED lengthPediatric patientsRevision codesCaregiver satisfactionProvider assessmentInternational ClassificationLower oddsPatientsNDD cohortPatient careSpecific developmental disordersDevelopment of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis
Gunasekera K, Marcy O, Muñoz J, Lopez-Varela E, Sekadde M, Franke M, Bonnet M, Ahmed S, Amanullah F, Anwar A, Augusto O, Aurilio R, Banu S, Batool I, Brands A, Cain K, Carratalá-Castro L, Caws M, Click E, Cranmer L, García-Basteiro A, Hesseling A, Huynh J, Kabir S, Lecca L, Mandalakas A, Mavhunga F, Myint A, Myo K, Nampijja D, Nicol M, Orikiriza P, Palmer M, Sant'Anna C, Siddiqui S, Smith J, Song R, Thuong Thuong N, Ung V, van der Zalm M, Verkuijl S, Viney K, Walters E, Warren J, Zar H, Marais B, Graham S, Debray T, Cohen T, Seddon J. Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: an individual participant data meta-analysis. The Lancet Child & Adolescent Health 2023, 7: 336-346. PMID: 36924781, PMCID: PMC10127218, DOI: 10.1016/s2352-4642(23)00004-4.Peer-Reviewed Original ResearchConceptsTreatment decision algorithmsPrimary health care settingsIndividual participant dataHigh tuberculosis incidencePulmonary tuberculosisManagement of tuberculosisHealth care centersComposite reference standardHealth care settingsClinical featuresTuberculosis incidenceClinical evaluationParticipant dataTreatment decisionsChest X-ray featuresPrimary health care centersFuture prospective evaluationTuberculosis-related mortalityEvidence-based algorithmChest X-rayVariable diagnostic performanceMultivariable prediction modelReference standardEvidence-based approachTuberculosis experts
2022
Evaluating musculoskeletal urgent care center triage and transfer of emergency conditions for emergency surgical assessment and intervention
Dlott C, Metcalfe T, Khunte A, Jain S, Bahel A, Hsiang W, Donnelley C, Kayani J, Wiznia D. Evaluating musculoskeletal urgent care center triage and transfer of emergency conditions for emergency surgical assessment and intervention. Medicine 2022, 101: e32519. PMID: 36595864, PMCID: PMC9794202, DOI: 10.1097/md.0000000000032519.Peer-Reviewed Original ResearchConceptsEmergency departmentCompartment syndromeLower extremity compartment syndromeExtremity compartment syndromeUrgent surgical interventionUrgent care centersDelay of careClinician suspicionEmergency surgeryJoint painOrthopedic emergencySurgical interventionAnkle sprainCare centerCritical patientsOrthopedic injuriesSurgical assessmentTriage questionsPrognostic studiesPatientsED resourcesOrthopedic conditionsReferral frequencyTriage practicesLevel IIWho Receives ICU Care during Times of Strain? Triage and the Potential for Racial Disparities
Jain S, Valley T. Who Receives ICU Care during Times of Strain? Triage and the Potential for Racial Disparities. Annals Of The American Thoracic Society 2022, 19: 1973-1974. PMID: 36454169, PMCID: PMC9743470, DOI: 10.1513/annalsats.202209-766ed.Peer-Reviewed Original ResearchUtilization of an Internal Medicine Triaging Resident in the Emergency Department Reduces Preventable Admissions and Improves Trainee Experiences
Saffo S, Rodwin B, Dalton R, Tarabar A, Merchant N. Utilization of an Internal Medicine Triaging Resident in the Emergency Department Reduces Preventable Admissions and Improves Trainee Experiences. Southern Medical Journal 2022, 115: 707-711. PMID: 36055659, DOI: 10.14423/smj.0000000000001434.Peer-Reviewed Original ResearchConceptsTransitions of careEmergency departmentHospital utilizationPreventable admissionsSingle-center pilot studyPatient safetyInitial patient managementIM traineesPatient care requirementsVeterans Affairs hospitalInternal medicine serviceGraduate Medical EducationIntegrated health systemInitial managementMedical admissionsED physiciansMedical patientsInpatient providersInpatient settingPatient managementTrainee experienceMedicine serviceCare requirementsED performance metricsSuboptimal communicationCORR Synthesis: What Triage Recommendations Are Available for Emergent or Urgent Musculoskeletal Conditions?
Dlott CC, Wiznia DH. CORR Synthesis: What Triage Recommendations Are Available for Emergent or Urgent Musculoskeletal Conditions? Clinical Orthopaedics And Related Research® 2022, 480: 1980-1988. PMID: 35901435, PMCID: PMC9473775, DOI: 10.1097/corr.0000000000002312.Peer-Reviewed Original ResearchEMS Non-Transport of Low-Risk COVID-19 Patients
Couturier K, Nelson AR, Burns K, Cone DC, Rollins M, Venkatesh AK, Ulrich A, Shapiro M, Joseph D. EMS Non-Transport of Low-Risk COVID-19 Patients. Prehospital Emergency Care 2022, 27: 310-314. PMID: 35639643, DOI: 10.1080/10903127.2022.2083278.Peer-Reviewed Original ResearchConceptsEMS cliniciansLow-risk COVID-19 patientsSuburban EMS systemLow-risk patientsED visit ratesEMS systemCOVID-19 patientsCOVID-19 infectionCOVID-19ED visitsRetrospective reviewEmergency departmentCOVID-19 casesProtocol violationsCommon reasonConnecticut OfficeHospital resourcesPatientsSmall studyVisit ratesVital signsHealth systemSymptomsReasonable adherenceCliniciansSurgical Triage and Timing for Patients With Coronavirus Disease: A Guidance Statement from The Society of Thoracic Surgeons
Grant M, Lother S, Engelman D, Hassan A, Atluri P, Moosdorf R, Hayanga J, Merritt-Genore H, Chatterjee S, Firstenberg M, Hirose H, Higgins J, Legare J, Lamarche Y, Kass M, Mansour S, Arora R. Surgical Triage and Timing for Patients With Coronavirus Disease: A Guidance Statement from The Society of Thoracic Surgeons. The Annals Of Thoracic Surgery 2022, 114: 387-393. PMID: 35595089, PMCID: PMC9113762, DOI: 10.1016/j.athoracsur.2022.05.001.Peer-Reviewed Original ResearchConceptsNew severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variantsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variantsCOVID-19Coronavirus disease 2019 (COVID-19) pandemicCardiac surgical teamPublic health effortsDisease 2019 pandemicPerioperative periodPreoperative patientsCOVID-19 casesVascular surgeryCritical careEfficacious vaccineCardiac surgeonsCardiovascular AngiographyThoracic Surgeons WorkforceThoracic surgeonsCardiac interventionsSurgical teamHealth effortsSurgical triageGuidance statementsInterventional cardiologyProcedural servicesCoronavirus diseaseSex and Race Differences in the Evaluation and Treatment of Young Adults Presenting to the Emergency Department With Chest Pain
Banco D, Chang J, Talmor N, Wadhera P, Mukhopadhyay A, Lu X, Dong S, Lu Y, Betensky RA, Blecker S, Safdar B, Reynolds HR. Sex and Race Differences in the Evaluation and Treatment of Young Adults Presenting to the Emergency Department With Chest Pain. Journal Of The American Heart Association 2022, 11: e024199. PMID: 35506534, PMCID: PMC9238573, DOI: 10.1161/jaha.121.024199.Peer-Reviewed Original ResearchConceptsChest painAcute myocardial infarctionEmergency departmentMultivariable adjustmentYoung adultsMyocardial infarctionBackground Acute myocardial infarctionRacial differencesCardiac biomarker testingHospital admissionClinical featuresConclusions WomenPhysician evaluationTriage levelBiomarker testingCardiac biomarkersWhite adultsNational estimatesObservation unitCP managementAdultsSurvey 2014WomenPainInfarction
2021
Reflections on New Evidence on Crisis Standards of Care in the COVID-19 Pandemic.
Tolchin B, Latham SR, Bruce L, Ferrante LE, Kraschel K, Jubanyik K, Hull SC, Herbst JL, Kapo J, Moritz ED, Hughes J, Siegel MD, Mercurio MR. Reflections on New Evidence on Crisis Standards of Care in the COVID-19 Pandemic. The Journal Of Clinical Ethics 2021, 32: 358-360. PMID: 34928864, DOI: 10.1086/jce2021324358.Commentaries, Editorials and LettersConceptsSOFA scoreBlack patientsCrisis standardsSequential Organ Failure Assessment scoreOrgan Failure Assessment scoreAccurate prognostic scoresNext public health emergencyCOVID-19 patientsLife-saving medical resourcesMedical resourcesCOVID-19 pandemicSame scoring systemPublic health emergencyPrognostic scoreBody of evidenceRare casePatientsScoring systemTriage purposesAssessment scoresHealth emergencyCareHealthcare systemCOVID-19ScoresThe Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good
Feder KJ, Zaidi D, Siegel MD. The Other Side of Triage: When Access to Intensive Care Measures May Do More Harm than Good. The American Journal Of Bioethics 2021, 21: 79-82. PMID: 34710018, DOI: 10.1080/15265161.2021.1980136.Peer-Reviewed Original ResearchEfficacy of Computer-Based Simulation as a Modality for Learning Pediatric Disaster Triage for Pediatric Emergency Nurses
Levy A, Khalil E, Chandramohan M, Whitfill T, Cicero M. Efficacy of Computer-Based Simulation as a Modality for Learning Pediatric Disaster Triage for Pediatric Emergency Nurses. Simulation In Healthcare The Journal Of The Society For Simulation In Healthcare 2021, 17: 329-335. PMID: 34652326, DOI: 10.1097/sih.0000000000000616.Peer-Reviewed Original ResearchConceptsPediatric emergency nursesPediatric disaster triageEmergency nursesTriage accuracyTertiary care emergency departmentProspective observational studyEmergency departmentPatient outcomesObservational studyEffective modalityNurse participantsNursing personnelDisaster triageHealthcare personnelScreen-based simulationMistriageEfficacy of computerNursesTriageEfficacyModalitiesSignificant improvementPoor resource utilizationEvaluation and disposition of older adults presenting to the emergency department with abdominal pain
Friedman AB, Chen AT, Wu R, Coe NB, Halpern SD, Hwang U, Kelz RR, Cappola AR. Evaluation and disposition of older adults presenting to the emergency department with abdominal pain. Journal Of The American Geriatrics Society 2021, 70: 501-511. PMID: 34628638, PMCID: PMC10078825, DOI: 10.1111/jgs.17503.Peer-Reviewed Original ResearchConceptsNational Hospital Ambulatory Medical Care SurveyAbdominal painUS emergency departmentsEmergency departmentED visitsOlder adultsOlder patientsChief complaintAmbulatory Medical Care SurveyRepresentative emergency departmentsCommon chief complaintSurvey-weighted analysisDischarge homeIncident disabilityED encountersCare SurveyPatient outcomesCritical careSerious conditionSyndromic presentationHigh riskPainDiagnostic testingPatientsCT imagingThe potential impact of triage protocols on racial disparities in clinical outcomes among COVID-positive patients in a large academic healthcare system
Roy S, Showstark M, Tolchin B, Kashyap N, Bonito J, Salazar MC, Herbst JL, Nash KA, Tiako M, Jubanyik K, Kim N, Galusha D, Wang KH, Oladele C. The potential impact of triage protocols on racial disparities in clinical outcomes among COVID-positive patients in a large academic healthcare system. PLOS ONE 2021, 16: e0256763. PMID: 34529684, PMCID: PMC8445412, DOI: 10.1371/journal.pone.0256763.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlack or African AmericanConnecticutCOVID-19Delivery of Health CareFemaleHealthcare DisparitiesHispanic or LatinoHospital MortalityHospitals, UniversityHumansMaleMiddle AgedOrgan Dysfunction ScoresPandemicsRetrospective StudiesSARS-CoV-2TriageWhite PeopleYoung AdultConceptsCOVID-positive patientsHigher SOFA scoreSOFA scoreClinical outcomesBlack patientsHospital mortalityICU admissionTriage protocolYale New Haven Health SystemSequential Organ Failure Assessment scoreHealthcare systemLarge academic healthcare systemOrgan Failure Assessment scoreRacial disparitiesSimilar clinical outcomesWorse clinical outcomesAcademic healthcare systemChi-square testRace/ethnicityPredictors of interestRetrospective cohortWhite patientsInsurance statusCOVID patientsTriage toolNeed for Emergent Intervention within 6 Hours: A Novel Prediction Model for Hospital Trauma Triage
Morris R, Karam BS, Zolfaghari EJ, Chen B, Kirsh T, Tourani R, Milia DJ, Napolitano L, de Moya M, Conterato M, Aliferis C, Ma S, Tignanelli C. Need for Emergent Intervention within 6 Hours: A Novel Prediction Model for Hospital Trauma Triage. Prehospital Emergency Care 2021, 26: 556-565. PMID: 34313534, DOI: 10.1080/10903127.2021.1958961.Peer-Reviewed Original ResearchAssociation of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient Outcomes
Khera R, Liu Y, de Lemos JA, Das SR, Pandey A, Omar W, Kumbhani DJ, Girotra S, Yeh RW, Rutan C, Walchok J, Lin Z, Bradley SM, Velazquez EJ, Churchwell KB, Nallamothu BK, Krumholz HM, Curtis JP. Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient Outcomes. The American Journal Of Medicine 2021, 134: 1380-1388.e3. PMID: 34343515, PMCID: PMC8325555, DOI: 10.1016/j.amjmed.2021.06.034.Peer-Reviewed Original ResearchConceptsCOVID-19 hospitalizationHospitalization volumeAmerican Heart Association COVID-19 Cardiovascular Disease RegistryCase volumeUS hospitalsCoronavirus disease 2019 (COVID-19) hospitalizationIntensive care unit therapyHospital case fatality ratePoor COVID-19 outcomesCardiovascular Disease RegistryHospital case volumeCase fatality rateCOVID-19 outcomesHospital bed capacityLowest quartilePatient outcomesHospital careHigher oddsTriage strategiesFuture health challengesDisease RegistryMedical treatmentEarly identificationHospitalSignificant association
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