2023
Recent ambient temperature and fine particulate matter (PM2.5) exposure is associated with urinary kidney injury biomarkers in children
Politis M, Gutiérrez-Avila I, Just A, Pizano-Zárate M, Tamayo-Ortiz M, Greenberg J, Téllez-Rojo M, Sanders A, Rosa M. Recent ambient temperature and fine particulate matter (PM2.5) exposure is associated with urinary kidney injury biomarkers in children. The Science Of The Total Environment 2023, 907: 168119. PMID: 37884142, PMCID: PMC10842020, DOI: 10.1016/j.scitotenv.2023.168119.Peer-Reviewed Original ResearchConceptsDistributed lag nonlinear modelParticulate matterAverage PM<sub>2.5</sub>Satellite-based spatio-temporal modelUrinary kidney injury biomarkersFine particulate matterExposure to ambient temperatureAir pollutionAerodynamic diameterBirth cohort studySpatio-temporal modelParticipating residentsCohort studyLimited researchEnvironmental exposuresMean temperatureDaily mean temperatureVisitsDaily temperatureAmbient temperatureMatterExposurePM2.5Linear regressionPollution
2022
Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study
Yao Y, Schneider A, Wolf K, Zhang S, Wang-Sattler R, Peters A, Breitner S. Longitudinal associations between metabolites and long-term exposure to ambient air pollution: Results from the KORA cohort study. Environment International 2022, 170: 107632. PMID: 36402035, DOI: 10.1016/j.envint.2022.107632.Peer-Reviewed Original ResearchConceptsLong-term exposure to air pollutionExposure to air pollutionLand-use regressionAir pollutionPhosphatidylcholine acyl-alkylParticulate matterLong-term exposure to ambient air pollutionAverage concentrations of ultrafine particlesExposure to ambient air pollutionEstimate annual average concentrationsAssociated with cardiopulmonary diseasesAmbient air pollutionConcentrations of ultrafine particlesPopulation-based Cooperative Health ResearchAmbient pollutantsLand-useAerodynamic diameterCooperative Health ResearchPollutionS4 surveyCoarse particlesFine particlesMixed-effects regression modelsUltrafine particlesNitrogen oxides
2021
Exposure to Primary Air Pollutants Generated by Highway Traffic and Daily Mortality Risk in Near-Road Communities: A Case-Crossover Study
Filigrana P, Milando C, Batterman S, Levy J, Mukherjee B, Pedde M, Szpiro A, Adar S. Exposure to Primary Air Pollutants Generated by Highway Traffic and Daily Mortality Risk in Near-Road Communities: A Case-Crossover Study. American Journal Of Epidemiology 2021, 191: 63-74. PMID: 34347034, DOI: 10.1093/aje/kwab215.Peer-Reviewed Original ResearchConceptsNear-road populationsAir pollutionMortality riskExposure to traffic-related air pollutionAverage PM2.5 exposureTraffic-generated air pollutionNear-road communitiesResearch LINE sourceConcentrations of PM2.5Traffic-related air pollutionCase-crossover designPrimary air pollutantsConditional logistic regressionPuget Sound area of Washington StateDaily mortality riskCase-crossoverTime-varying covariatesCerebrovascular mortalityPM2.5 exposurePrimary pollutantsQuantify associationsAerodynamic diameterShorter averaging periodsPM2.5PollutionAerosol and Droplet Risk of Common Otolaryngology Clinic Procedures
Boorgu DSSK, Dharmarajan H, Sim ES, Goyal L, Freiser ME, Weinstock M, Whelan R, Corcoran TE, Jabbour N, Wang E, H. D. Aerosol and Droplet Risk of Common Otolaryngology Clinic Procedures. Annals Of Otology Rhinology & Laryngology 2021, 130: 1245-1253. PMID: 33730891, DOI: 10.1177/00034894211000502.Peer-Reviewed Original ResearchConceptsPersonal protective equipmentNasal endoscopyClinic proceduresExternal earRigid nasal endoscopyPositive controlOpen suctioningFluorescent tracersNasal suctionRetrograde intubationBaseline riskNasal cavityAerodynamic diameterProtective equipmentCadaveric headsEndoscopyAdditional riskCOVID-19 eraEndonasal drillingClinical proceduresSuctioningRiskVitamin B2BreathingDroplet contamination
2020
Attributable risk and economic cost of hospital admissions for mental disorders due to PM2.5 in Beijing
Wu Z, Chen X, Li G, Tian L, Wang Z, Xiong X, Yang C, Zhou Z, Pan X. Attributable risk and economic cost of hospital admissions for mental disorders due to PM2.5 in Beijing. The Science Of The Total Environment 2020, 718: 137274. PMID: 32109812, PMCID: PMC9429815, DOI: 10.1016/j.scitotenv.2020.137274.Peer-Reviewed Original ResearchConceptsHospital admissionAttributable riskMental disordersEconomic burdenSignificant risk increaseMental health statusEffects of PMSubstantial morbidityStratified analysisElderly individualsHealth statusMedical expensesStudy periodAir quality guidelinesRisk increaseAdmissionTime trendsRiskEconomic costsDisordersPossible correlationBurdenAerodynamic diameterExposureDaily increaseHourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany
Chen K, Schneider A, Cyrys J, Wolf K, Meisinger C, Heier M, von Scheidt W, Kuch B, Pitz M, Peters A, Breitner S, Group F. Hourly Exposure to Ultrafine Particle Metrics and the Onset of Myocardial Infarction in Augsburg, Germany. Environmental Health Perspectives 2020, 128: 017003. PMID: 31939685, PMCID: PMC7015564, DOI: 10.1289/ehp5478.Peer-Reviewed Original ResearchConceptsMyocardial infarctionMI casesTime-stratified case-crossover analysisConditional logistic regressionInterquartile range increaseCase-crossover analysisTwo-pollutant modelsMI registryEpidemiological evidenceDifferent particle metricsCardiovascular diseaseMyocardial infractionSimilar associationLogistic regressionHourly air pollutionParticle metricsEffect estimatesHealth effectsExposure metricsIndependent effectsTransient exposureInfarctionAssociationExposureAerodynamic diameter
2018
Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization
Zhang S, Breitner S, Cascio W, Devlin R, Neas L, Diaz-Sanchez D, Kraus W, Schwartz J, Hauser E, Peters A, Schneider A. Short-term effects of fine particulate matter and ozone on the cardiac conduction system in patients undergoing cardiac catheterization. Particle And Fibre Toxicology 2018, 15: 38. PMID: 30305173, PMCID: PMC6180522, DOI: 10.1186/s12989-018-0275-z.Peer-Reviewed Original ResearchConceptsAssociations of PM2.5Particulate matterAir pollutionShort-term exposure to air pollutionDaily concentrations of PM2.5Short-term effects of particulate matterEffects of fine particulate matterShort-term effects of fine particulate matterExposure to air pollutionEffects of particulate matterConcentrations of PM2.5Fine particulate matterPollution-induced changesAir pollution effectsInvestigate short-term effectsDaily concentrationsPM2.5Pollution effectsAssociation of O3Temporal lag structureAerodynamic diameterDistributed-lag modelParticipant's home addressExposure modelO3Long-term effects of air pollution on ankle-brachial index
Zhang S, Wolf K, Breitner S, Kronenberg F, Stafoggia M, Peters A, Schneider A. Long-term effects of air pollution on ankle-brachial index. Environment International 2018, 118: 17-25. PMID: 29787898, DOI: 10.1016/j.envint.2018.05.025.Peer-Reviewed Original ResearchConceptsEffects of air pollutionLong-term exposure to PMExposure to PMAir pollutionParticulate matterLong-term exposure to air pollutionAdverse effects of air pollutionLand-use regression modelsLong-term effects of air pollutionExposure to air pollutionAnnual mean concentrationsHigh ankle-brachial indexAnkle-brachial indexAbnormal ankle-brachial indexLand-useMean concentrationsAerodynamic diameterPollutionNitrogen dioxideGeographic information systemPercentile incrementOdds ratioPrevalence of low ankle-brachial indexRegression modelsRegion of Augsburg
2017
Pregnancy and Lifetime Exposure to Fine Particulate Matter and Infant Mortality in Massachusetts, 2001–2007
Son JY, Lee HJ, Koutrakis P, Bell ML. Pregnancy and Lifetime Exposure to Fine Particulate Matter and Infant Mortality in Massachusetts, 2001–2007. American Journal Of Epidemiology 2017, 186: 1268-1276. PMID: 29121205, PMCID: PMC5860580, DOI: 10.1093/aje/kwx015.Peer-Reviewed Original ResearchConceptsSudden infant death syndrome mortalityInfant mortalityLifetime exposurePM2.5 exposurePostneonatal infant mortalityExtended Cox proportional hazardsCox proportional hazardsInterquartile range increaseTime-dependent covariatesHazard ratioGestational exposureGestational lengthSeason of birthBirth weightMaternal characteristicsShort-term exposureProportional hazardsMortalityPregnancyBirthExposureSupportive evidenceDeathFine particulate matterAerodynamic diameterAssociations between mortality and prolonged exposure to elevated particulate matter concentrations in East Asia
Kim SE, Bell ML, Hashizume M, Honda Y, Kan H, Kim H. Associations between mortality and prolonged exposure to elevated particulate matter concentrations in East Asia. Environment International 2017, 110: 88-94. PMID: 29097051, DOI: 10.1016/j.envint.2017.10.010.Peer-Reviewed Original ResearchInvestigating the Impact of Maternal Residential Mobility on Identifying Critical Windows of Susceptibility to Ambient Air Pollution During Pregnancy
Warren JL, Son JY, Pereira G, Leaderer BP, Bell ML. Investigating the Impact of Maternal Residential Mobility on Identifying Critical Windows of Susceptibility to Ambient Air Pollution During Pregnancy. American Journal Of Epidemiology 2017, 187: 992-1000. PMID: 29053768, PMCID: PMC5928458, DOI: 10.1093/aje/kwx335.Peer-Reviewed Original ResearchConceptsLow birth weightTerm low birth weightMaternal residential mobilityBirth weightCritical windowBirth cohortWeekly exposurePregnancy week 16Adverse birth outcomesWindow of susceptibilityAmbient air pollutionPregnancy windowsBirth outcomesWeek 16Mother's residencePM10 exposurePregnancyResidential addressesExposure misclassificationDisease developmentCohortAir pollutionExposureAerodynamic diameterPossible mechanismParticulate Matter and Risk of Hospital Admission in the Kathmandu Valley, Nepal: A Case-Crossover Study
Gurung A, Son JY, Bell ML. Particulate Matter and Risk of Hospital Admission in the Kathmandu Valley, Nepal: A Case-Crossover Study. American Journal Of Epidemiology 2017, 186: 573-580. PMID: 28911012, DOI: 10.1093/aje/kwx135.Peer-Reviewed Original ResearchConceptsHealth burdenTime-stratified case-crossover analysisRisk of hospitalizationSubstantial health burdenInpatient hospitalization dataCase-crossover studyPotential effect modifiersCase-crossover analysisMajority of evidenceHospital admissionEffect modificationCardiovascular admissionsHospitalization dataM3 increaseEffect modifiersMajor hospitalsSocioeconomic statusHospitalizationAdmissionHuman health burdenKathmandu ValleyCentral data collection systemBurdenAir pollutionAerodynamic diameter
2015
Air pollution and mortality in São Paulo, Brazil: Effects of multiple pollutants and analysis of susceptible populations
Bravo MA, Son J, de Freitas CU, Gouveia N, Bell ML. Air pollution and mortality in São Paulo, Brazil: Effects of multiple pollutants and analysis of susceptible populations. Journal Of Exposure Science & Environmental Epidemiology 2015, 26: 150-161. PMID: 25586330, DOI: 10.1038/jes.2014.90.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAir PollutantsAir PollutionBrazilCarbon MonoxideCardiovascular DiseasesCase-Control StudiesDeath CertificatesEnvironmental MonitoringFemaleHumansLogistic ModelsMaleMiddle AgedNitrogen DioxideOzoneParticle SizeParticulate MatterRespiratory Tract DiseasesRisk FactorsSex DistributionSocioeconomic FactorsSulfur DioxideConceptsTime of deathSocioeconomic statusTime-stratified case-crossover analysisCase-crossover analysisResidential socioeconomic statusEducation groupHospital deathCardiovascular mortalityNon-accidental mortalityRespiratory mortalityMortality riskHigh education groupEvidence of differencesSignificant associationMortalityEffect estimatesDeathMortality effectsSusceptible populationHealth impactsAmbient monitorsIndividual-level health dataAir pollutionHealth dataAerodynamic diameter
2014
Air Quality in Lanzhou, a Major Industrial City in China: Characteristics of Air Pollution and Review of Existing Evidence from Air Pollution and Health Studies
Zhang Y, Li M, Bravo MA, Jin L, Nori-Sarma A, Xu Y, Guan D, Wang C, Chen M, Wang X, Tao W, Qiu W, Zhang Y, Bell ML. Air Quality in Lanzhou, a Major Industrial City in China: Characteristics of Air Pollution and Review of Existing Evidence from Air Pollution and Health Studies. Water, Air, & Soil Pollution 2014, 225: 2187. PMID: 25838615, PMCID: PMC4380132, DOI: 10.1007/s11270-014-2187-3.Peer-Reviewed Original ResearchGlobal health burdenSerious health consequencesFuture epidemiological studiesOutdoor air pollutionHealth burdenEpidemiological studiesHealth StudyHealth outcomesSystematic reviewHealth consequencesHigh air pollution levelsAir pollutionMonthsAir pollution levelsAerodynamic diameterHealthReviewUrban Chinese citiesHealth-based standardsLevelsStudyFindingsThe characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures
Morishita M, Bard R, Wang L, Das R, Dvonch J, Spino C, Mukherjee B, Sun Q, Harkema J, Rajagopalan S, Brook R. The characteristics of coarse particulate matter air pollution associated with alterations in blood pressure and heart rate during controlled exposures. Journal Of Exposure Science & Environmental Epidemiology 2014, 25: 153-159. PMID: 25227729, PMCID: PMC4462122, DOI: 10.1038/jes.2014.62.Peer-Reviewed Original ResearchConceptsCoarse PMPM massEffects of coarse PMCoarse PM massAmbient coarse PMRural locationsSystolic BPMetrics of exposureBlood pressurePotential health effectsHeart ratePM elementsElevated systolic BPFiltered airAerodynamic diameterDiastolic BP changesMixed model analysisConcentration-response mannerParticulate massFilter samplesParticle constituentsDiastolic BPMeasured elementsHealthy adultsAssociated with similar degrees
2013
Development of a job-exposure matrix for exposure to total and fine particulate matter in the aluminum industry
Noth EM, Dixon-Ernst C, Liu S, Cantley L, Tessier-Sherman B, Eisen EA, Cullen MR, Hammond SK. Development of a job-exposure matrix for exposure to total and fine particulate matter in the aluminum industry. Journal Of Exposure Science & Environmental Epidemiology 2013, 24: 89-99. PMID: 24022670, PMCID: PMC4067135, DOI: 10.1038/jes.2013.53.Peer-Reviewed Original ResearchConceptsJob-exposure matrixOccupational exposureHigh occupational exposureTPM exposureCardiovascular diseaseEpidemiologic studiesExposure groupPM2.5 exposureExposure metricsPM2.5 exposure concentrationsHealth impactsPersonal monitoringTPM concentrationsExposure concentrationsExposureFine particulate matterTPM samplesAerodynamic diameterTotal PMMean PM2.5 concentrationsDisease
2012
Air pollution and respiratory symptoms among children with asthma: Vulnerability by corticosteroid use and residence area
Lewis T, Robins T, Mentz G, Zhang X, Mukherjee B, Lin X, Keeler G, Dvonch J, Yip F, O'Neill M, Parker E, Israel B, Max P, Reyes A, Committee C. Air pollution and respiratory symptoms among children with asthma: Vulnerability by corticosteroid use and residence area. The Science Of The Total Environment 2012, 448: 48-55. PMID: 23273373, PMCID: PMC4327853, DOI: 10.1016/j.scitotenv.2012.11.070.Peer-Reviewed Original ResearchConceptsParticulate matterAir pollutionAssociated with negative health impactsAmbient pollutant concentrationsAir quality standardsAmbient air pollutionAmbient particulate matterEffective risk reduction interventionsOdds of respiratory symptomsAsthmatic childrenFactors associated with heterogeneityAssociated with increased oddsObserved health effectsRespiratory symptomsRisk reduction interventionsPopulation of asthmatic childrenRespiratory symptom diariesOutdoor PMDaily concentrationsPollutant concentrationsMonitoring sitesGeneralized estimating equationsPollution modelLogistic regression modelsAerodynamic diameterAssessment of the health impacts of particulate matter characteristics.
Bell ML. Assessment of the health impacts of particulate matter characteristics. Research Report 2012, 5-38. PMID: 22393584.Peer-Reviewed Original ResearchConceptsHealth effect estimatesCardiovascular hospital admissionsHospital admissionEffect estimatesMortality effect estimatesHealth effectsCause of hospitalizationAir pollution-related health effectsInterquartile range increasePollution-related health effectsRespiratory hospital admissionsAdverse health effectsHealth effects dataCardiovascular hospitalizationRespiratory hospitalizationsCardiovascular admissionsHigh prevalenceHospitalizationAerodynamic diameterAdmissionCommunity-level variablesObserved associationsSocioeconomic statusHealth impactsPM toxicity
2008
Coarse Particulate Matter Air Pollution and Hospital Admissions for Cardiovascular and Respiratory Diseases Among Medicare Patients
Peng RD, Chang HH, Bell ML, McDermott A, Zeger SL, Samet JM, Dominici F. Coarse Particulate Matter Air Pollution and Hospital Admissions for Cardiovascular and Respiratory Diseases Among Medicare Patients. JAMA 2008, 299: 2172-2179. PMID: 18477784, PMCID: PMC3169813, DOI: 10.1001/jama.299.18.2172.Peer-Reviewed Original ResearchConceptsRespiratory disease admissionsHospital admissionRespiratory diseaseAdmission ratesM3 increaseEmergency hospital admissionsCardiovascular disease admissionsParticulate matter air pollutionSame-day exposureMatter air pollutionHealth risksMedicare's National Claims History FilePrimary diagnosisMedicare patientsUnadjusted associationsCardiovascular diseaseStudy populationAdmissionAerodynamic diameterMedicare enrolleesSignificant associationDaily cardiovascularDiseaseSame dayPM10-2.5
2007
Potential Confounding of Particulate Matter on the Short-Term Association between Ozone and Mortality in Multisite Time-Series Studies
Bell ML, Kim JY, Dominici F. Potential Confounding of Particulate Matter on the Short-Term Association between Ozone and Mortality in Multisite Time-Series Studies. Environmental Health Perspectives 2007, 115: 1591-1595. PMID: 18007990, PMCID: PMC2072830, DOI: 10.1289/ehp.10108.Peer-Reviewed Original ResearchConceptsPotential confoundingShort-term effectsMultisite time-series studyShort-term associationsMortality associationLikely confoundersU.S. urban communitiesShort-term exposureStudy daysTime-series studyMortalityStudy periodEffect estimatesConfoundersFurther investigationAssociationAmbient exposureMortality relationshipConfoundingDaysAerodynamic diameterExposureCovariatesDaily PM concentrationsUrban communities
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